Document Detail


Comparison of two Papanicolaou staining procedures for automated prescreening.
MedLine Citation:
PMID:  94777     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A "regressive" (procedure I) and a "progressive" (procedure II) modification of the Papanicolaou stain were tested for their suitability for automated screening procedures. Intermediate squamous cells and carcinoma cells were scanned with a high-resolution system, and digitized data were statistically analyzed after feature extraction. The regressive modification accentuates the textural features of intermediate squamous cell nuclei as well as the contrast ratio of nucleus and cytoplasm. The progressive modification accentuates some criteria of malignancy, such as polychromasia, hyperchromasia and shifting of nuclear to cytoplasmic ratio. Grouping of data according to patients indicates that the differences found are due to the staining procedures and not to individual variability of parameters in different patients.
Authors:
H J Soost; E W Falter; K Otto
Related Documents :
10225457 - Evidence of lmp1-traf3 interactions in glycosphingolipid-rich complexes of lymphoblasto...
17571237 - High expression of integrin beta1 correlates with high proliferation capacity in oral k...
20633287 - Human papillomavirus-mediated carcinogenesis and hpv-associated oral and oropharyngeal ...
7874697 - The influence of the cysteine protease inhibitor l-trans-epoxysuccinyl-leucyl amido(4-g...
20857517 - Fluoxetine promotes gliogenesis during neural differentiation in mouse embryonic stem c...
19385037 - Feed-back regulation of successive meiotic cytokinesis.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Analytical and quantitative cytology     Volume:  1     ISSN:  0190-0471     ISO Abbreviation:  Anal Quant Cytol     Publication Date:    1979 Mar-Apr
Date Detail:
Created Date:  1980-07-28     Completed Date:  1980-07-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7911206     Medline TA:  Anal Quant Cytol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  37-42     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Autoanalysis
Cell Nucleus / ultrastructure
Cervix Uteri / cytology*
Chromatin / analysis
Cytological Techniques*
Female
Humans
Photometry
Staining and Labeling / methods*
Uterine Cervical Neoplasms / diagnosis*,  pathology
Vaginal Smears*
Chemical
Reg. No./Substance:
0/Chromatin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cyclic AMP in hypersensitivity reactions.
Next Document:  The monodisperse cervical smear: quantitative analysis of cell dispersion and loss with enzymatic an...