| Comparison of two Papanicolaou staining procedures for automated prescreening. | |
MedLine Citation:
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PMID: 94777 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A "regressive" (procedure I) and a "progressive" (procedure II) modification of the Papanicolaou stain were tested for their suitability for automated screening procedures. Intermediate squamous cells and carcinoma cells were scanned with a high-resolution system, and digitized data were statistically analyzed after feature extraction. The regressive modification accentuates the textural features of intermediate squamous cell nuclei as well as the contrast ratio of nucleus and cytoplasm. The progressive modification accentuates some criteria of malignancy, such as polychromasia, hyperchromasia and shifting of nuclear to cytoplasmic ratio. Grouping of data according to patients indicates that the differences found are due to the staining procedures and not to individual variability of parameters in different patients. |
Authors:
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H J Soost; E W Falter; K Otto |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Analytical and quantitative cytology Volume: 1 ISSN: 0190-0471 ISO Abbreviation: Anal Quant Cytol Publication Date: 1979 Mar-Apr |
Date Detail:
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Created Date: 1980-07-28 Completed Date: 1980-07-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7911206 Medline TA: Anal Quant Cytol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 37-42 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Autoanalysis Cell Nucleus / ultrastructure Cervix Uteri / cytology* Chromatin / analysis Cytological Techniques* Female Humans Photometry Staining and Labeling / methods* Uterine Cervical Neoplasms / diagnosis*, pathology Vaginal Smears* |
| Chemical | |
Reg. No./Substance:
|
0/Chromatin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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