| Comparison of total oxidant/antioxidant status in unconjugated hyperbilirubinemia of newborn before and after conventional and LED phototherapy: A prospective randomized controlled trial. | |
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MedLine Citation:
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PMID: 20926040 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: We evaluated and compared the oxidant and antioxidant status of hyperbilirubinemic infants before and after the two forms of phototherapy: conventional and LED phototherapy, in order to identify the optimal treatment method. METHOD: Thirty newborns exposed to conventional (Group I) phototherapy and 30 infants exposed to LED phototherapy (Group II) were studied. The serum total antioxidant capacity (TAC) and the total oxidant status (TOS) were assessed by EREL's method. RESULTS: There were no statistically significant differences in TAC or TOS levels between Group I and Group II prior to phototherapy, and no statistically significant difference in TAC levels between the two groups after phototherapy; however, TOS levels were significantly lower in Group II compared to Group I after phototherapy. Oxidative stress index (OSI) increased after conventional phototherapy (p < 0.05) CONCLUSION: The increase in TOS following conventional phototherapy was not not observed following LED phototherapy. This difference should be considered when using phototherapy. |
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Authors:
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Gamze Demirel; Nurdan Uras; Istemi H Celik; Hatice T Aksoy; Serife S Oguz; Omer Erdeve; Ozcan Erel; Ugur Dilmen |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial Date: 2010-10-01 |
Journal Detail:
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Title: Clinical and investigative medicine. Médecine clinique et experimentale Volume: 33 ISSN: 1488-2353 ISO Abbreviation: Clin Invest Med Publication Date: 2010 |
Date Detail:
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Created Date: 2010-10-07 Completed Date: 2011-01-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7804071 Medline TA: Clin Invest Med Country: Canada |
Other Details:
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Languages: eng Pagination: E335-41 Citation Subset: IM |
Affiliation:
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Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey. kgamze@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antioxidants
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metabolism* Humans Hyperbilirubinemia / blood*, metabolism, therapy* Infant, Newborn Oxidants / blood* Phototherapy* |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Oxidants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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