Document Detail


Comparison of thyroid volume and goiter measured by means of ultrasonography and SPECT with use of 131I and 99m)c in smokers and non-smokers.
MedLine Citation:
PMID:  20041360     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: The aim of the study was to estimate the influence of nicotine on thyroid volume according to patients' sex. MATERIAL AND METHODS: A group of 160 patients with thyroid disorders in their past medical history was examined. Patients were divided into two groups: Group A contained 50 patients with goiter, where the volume of the thyroid was evaluated with use of US and (131)I-SPECT; group B contained 50 patients with goiter, where the volume of the thyroid was evaluated with use of US and (99m)Tc-SPECT. There were two control groups: Group A' contained 30 patients with normal volume of the thyroid gland shown by US and (131)I-SPECT, and group B' contained 30 patients with normal volume of the thyroid gland shown by US and (99m)Tc-SPECT. The patients from the examined and control groups were divided into two subgroups - smokers and non-smokers. US of the thyroid gland was made by means of an ALOKA SSD 500 device. SPECT was performed by means of a singke-headed gamma camera by Diacam. RESULTS: The average volume of thyroid gland measured by (131)I-SPECT and (99m)Tc-SPECT was significantly larger according to US in the examined and control groups in smokers and non-smokers. We did not show statistically significant correlations between levels of iodine uptake and volumes of goiter evaluated by US examination together with (131)I scintigraphy. CONCLUSIONS: Significant differences in average values of thyroid volume between smokers and non-smokers were not observed, which might suggest a lack of goitrogenic activity of tobacco smoke or indicates a potential goitrogenic influence not significant enough in the examined group.
Authors:
Marcin Gierach; Joanna Gierach; Roman Junik
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Endokrynologia Polska     Volume:  60     ISSN:  0423-104X     ISO Abbreviation:  Endokrynol Pol     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2009-12-30     Completed Date:  2010-04-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370674     Medline TA:  Endokrynol Pol     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  437-42     Citation Subset:  IM    
Affiliation:
Laboratory of Nuclear Medicine of the Department of Endocrinology and Diabetology, Nicolaus Copernicus University, Torun, Collegium Medicum, Bydgoszcz, Bydgoszcz, Poland. marcin_gierach@wp.pl
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MeSH Terms
Descriptor/Qualifier:
Comorbidity
Female
Goiter / epidemiology*,  pathology,  ultrasonography*
Humans
Iodine Radioisotopes / diagnostic use
Male
Middle Aged
Organ Size
Sex Distribution
Smoking / epidemiology*
Technetium / diagnostic use
Thyroid Gland / pathology,  ultrasonography*
Tomography, Emission-Computed, Single-Photon
Chemical
Reg. No./Substance:
0/Iodine Radioisotopes; 7440-26-8/Technetium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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