| Comparison of three methods for detection of the lactate threshold. | |
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MedLine Citation:
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PMID: 17944661 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The lactate threshold (LT) represents the onset of a metabolic acidosis during graded exercise testing (GXT). It is a valuable measurement in clinical exercise testing and correlates well with endurance performance. Our purpose was to compare three LT detection methods, namely, Inspection (work rate at onset of a systematic increase in blood lactate concentration determined by inspection of blood lactate versus work rate plot), 0.5 mM (work rate which just precedes a rise in blood lactate concentration of >0.5 mM) and log-log (work rate at the intersection of two linear lines in plot of log lactate versus log work rate where the residual sum of squares for both lines added together is minimized). Fourteen subjects underwent cycle ergometer GXT with blood samples obtained at the end of each 3-min work rate increment and analysed for lactate concentration. The mean +/- 95% confidence limits of work rates at LT for the Inspection, 0.5 mM and log-log methods were 104.5 +/- 28.0, 103.2 +/- 28.1 and 105.1 +/- 27.3 W, respectively. Repeated-measures analysis of variance yielded a non-significant F ratio. The Bland-Altman bias +/- 95% limits of agreement for Inspection versus 0.5 mM, Inspection versus log-log and 0.5 mM versus log-log were 1.3 +/- 20.6, -0.6 +/- 12.5 and -1.9 +/- 20.5 W, respectively. The intraclass correlation coefficients for Inspection versus 0.5 mM, Inspection versus log-log and 0.5 mM versus log-log were 0.978, 0.992 and 0.977, respectively. The results of this study suggest that all three methods detect the LT at the same work rate. |
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Authors:
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James A Davis; Ralph Rozenek; Derek M DeCicco; Michael T Carizzi; Patrick H Pham |
Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinical physiology and functional imaging Volume: 27 ISSN: 1475-0961 ISO Abbreviation: Clin Physiol Funct Imaging Publication Date: 2007 Nov |
Date Detail:
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Created Date: 2007-10-19 Completed Date: 2007-12-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101137604 Medline TA: Clin Physiol Funct Imaging Country: England |
Other Details:
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Languages: eng Pagination: 381-4 Citation Subset: IM |
Affiliation:
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Laboratory of Applied Physiology, Department of Kinesiology, California State University/Long Beach, Long Beach, CA 90840-4901, USA. jad@csulb.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Algorithms* Anaerobic Threshold / physiology* Blood Chemical Analysis / methods* Differential Threshold / physiology Exercise Test / methods* Female Humans Lactic Acid / blood* Male Reproducibility of Results Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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50-21-5/Lactic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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