Document Detail

Comparison of three different iodine-based bowel regimens for CT colonography.
MedLine Citation:
PMID:  19711082     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The aim of this study was to compare the computed tomographic colonography (CTC) image quality and patient acceptance of three iodine-based faecal tagging bowel preparations in 60 patients undergoing the following regimens: a 2-day regimen of meal-time administration of iodine and phospho-soda (GFPH); a 2-day regimen of meal-time mild laxative, followed by iodine administered 2 h before CTC (SD); and a 2-day regimen of meal-time administration of iodine (GF). METHODS: Two independent radiologists assessed tagging quality; quantitative measures included the tagged stool density, and computer-aided detection (CAD) false-positive rate. RESULTS: The GFPH and SD regimens provided better subjective quality than GF (p < 0.001). The latter regimen resulted in a higher proportion of insufficiently tagged segments: the measured average stool density was less than 200 HU in 10.7% in all segments vs 3.6% for SD and <0.5% for GFPH, respectively. Insufficient tagging occurred mostly in the ascending colon and the caecum. The CAD false-positive rate increased following the trend: GFPH < SD < GF (p = 0.00012). GFPH was worse tolerated than SD (p < 0.05). CONCLUSIONS: Considering preparation quality alone, GFPH was the best regimen, but SD provided the best balance between bowel preparation quality and patient acceptability.
Delia Campanella; Lia Morra; Silvia Delsanto; Vincenzo Tartaglia; Roberto Asnaghi; Alberto Bert; Emanuele Neri; Daniele Regge
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2009-08-27
Journal Detail:
Title:  European radiology     Volume:  20     ISSN:  1432-1084     ISO Abbreviation:  Eur Radiol     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-01     Completed Date:  2010-04-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  348-58     Citation Subset:  IM    
Radiology Unit, Institute for Cancer Research and Treatment, Strada Provinciale 142, Km 3,95, 10060 Candiolo, Italy.
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MeSH Terms
Aged, 80 and over
Attitude to Health*
Colonography, Computed Tomographic / methods*
Colorectal Neoplasms / radiography*
Contrast Media
Drug Administration Schedule
Intestines / radiography*
Iodine / administration & dosage*,  diagnostic use*
Middle Aged
Patient Acceptance of Health Care*
Reproducibility of Results
Sensitivity and Specificity
Reg. No./Substance:
0/Contrast Media; 7553-56-2/Iodine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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