Document Detail


Comparison of thiopentone sodium and propofol for electro convulsive therapy (ECT).
MedLine Citation:
PMID:  10769525     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: For safe conduct of electro convulsive therapy (ECT), general anaesthesia is administered to the patients. In this study we compared thiopentone sodium and propofol as induction agents for ECT. PATIENTS AND METHODS: Twenty five patients each undergoing at least 2 sessions of ECT at the psychiatry department were included in the study. Each patient either received thiopentone or propofol for induction of sleep in a randomized manner. Drugs were evaluated regarding their effects on ECT induced haemodynamic changes (Blood pressure, Heart rate), seizure duration related to the procedure and recovery from sleep. Any side effects during the procedure and recovery were also noted. RESULTS: Propofol offered a superior haemodynamic stability during the procedure and a quick recovery from sleep. CONCLUSION: Propofol was found to be a better induction agent for ECT compared to thiopentone sodium.
Authors:
N A Zaidi; F A Khan
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  JPMA. The Journal of the Pakistan Medical Association     Volume:  50     ISSN:  0030-9982     ISO Abbreviation:  J Pak Med Assoc     Publication Date:  2000 Feb 
Date Detail:
Created Date:  2000-05-16     Completed Date:  2000-05-16     Revised Date:  2008-02-12    
Medline Journal Info:
Nlm Unique ID:  7501162     Medline TA:  J Pak Med Assoc     Country:  PAKISTAN    
Other Details:
Languages:  eng     Pagination:  60-3     Citation Subset:  IM    
Affiliation:
Department of Anaesthesiology and Intensive care, Aga Khan University Hospital, Karachi.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anesthesia, Intravenous*
Anesthetics, Intravenous*
Electrocardiography
Electroconvulsive Therapy / methods*
Female
Humans
Male
Mood Disorders / therapy*
Propofol*
Thiopental*
Chemical
Reg. No./Substance:
0/Anesthetics, Intravenous; 2078-54-8/Propofol; 76-75-5/Thiopental

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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