Document Detail

Comparison study of central blood pressure and wave reflection obtained from tonometry-based devices.
MedLine Citation:
PMID:  23382325     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND Although tonometry-based devices have been applied in several population studies and clinical trials, the agreement between them remains unclear. METHODS Carotid systolic blood pressure (SBP) and augmentation index (AI) were randomly measured from 3 devices, SphygmoCor, PulsePen, and A-Pulse, in 66 consecutive patients from our ambulatory cardiovascular department. The study contains 2 phases: in Study 1, SphygmoCor and PulsePen were performed on each participant by 2 experienced physicians (n = 66); in Study 2, A-Pulse was added after the measurements of SphygmoCor and PulsePen and performed by another technician on the last 34 patients. RESULTS Carotid SBP and AI measured by the 3 devices were strongly correlated (R ≥ 0.78; P < 0.001), but with significant discrepancies. Specifically, in 66 participants of Study 1, PulsePen estimated higher carotid SBP and AI by 5mm Hg and 5.7%, respectively, than SphygmoCor. In 34 patients of Study 2, A-Pulse estimated higher central SBP by 3.7mm Hg than SphygmoCor, and lower central SBP by 5.7mm Hg than PulsePen. However, no significant difference in interclass comparison was detected between the 3 devices (P ≥ 0.26). Furthermore, slopes of correlation plots of parameters between SphygmoCor and PulsePen were not significantly different from 1 (P ≥ 0.09), but were different in the case of A-Pulse (P ≤ 0.004). CONCLUSIONS Tonometry-based devices were not consistent in measurements of central BP and wave reflections in clinical practice, with considerable and significant differences among them. However, in contrast to A-Pulse, SphygmoCor and PulsePen can probably assess similar cardiovascular risk for individuals, with a systematical discrepancy.
Yi Zhang; Davide Agnoletti; Michel E Safar; Ji-Guang Wang; Jirar Topouchian; Yawei Xu; Athanase D Protogerou; Jacques Blacher
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of hypertension     Volume:  26     ISSN:  1941-7225     ISO Abbreviation:  Am. J. Hypertens.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-02-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8803676     Medline TA:  Am J Hypertens     Country:  United States    
Other Details:
Languages:  eng     Pagination:  34-41     Citation Subset:  IM    
Department of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
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