| Comparison of standard, prone and cine MRI in the evaluation of tethered cord. | |
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MedLine Citation:
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PMID: 22143965 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Tethered cord syndrome (TCS) is defined by abnormal traction on the spinal cord that confines its movement. Surgical cord release usually stops neurological deterioration; therefore, early and accurate neuroradiological diagnosis is important. Supine MRI is the imaging modality of choice, but prone MRI and cine MRI can demonstrate cord movement. OBJECTIVE: We compared the diagnostic accuracies of standard MRI, prone MRI and cine MRI in patients with clinical suspicion of TCS and evaluated inter-reader reliability for MR imaging. MATERIALS AND METHODS: Children who underwent MRI for suspicion of TCS were retrospectively identified. Supine, prone and cine MRI studies were re-read by two pediatric neuroradiologists. Conus level, filum appearance and cord movement were documented. RESULTS: Thirteen of 49 children had tethered cord documented at surgery. Conus level had the highest diagnostic accuracy (sensitivity 69-77%, specificity 94%, positive predictive value 82-83%, negative predictive value 89-92%, correct diagnosis 88-90%) and highest between-reader concordance (98%). Prone and cine MRI did not add to the accuracy of the supine imaging. CONCLUSION: Conus level provides the highest diagnostic accuracy and inter-reader reliability in TCS. Until a larger series is evaluated, it remains questionable whether prone or cine MRI provides enough additional diagnostic information to warrant routine use. |
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Authors:
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Sukhjinder Singh; Beth Kline-Fath; Karin Bierbrauer; Judy M Racadio; Shelia Salisbury; Maurizio Macaluso; Elizabeth C Jackson; John C Egelhoff |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-6 |
Journal Detail:
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Title: Pediatric radiology Volume: - ISSN: 1432-1998 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-6 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0365332 Medline TA: Pediatr Radiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Radiology, Cohen Children's Medical Center, New Hyde Park, NY, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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