Document Detail

Comparison of spherical aberration and small-pupil profiles in improving depth of focus for presbyopic corrections.
MedLine Citation:
PMID:  23031641     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To compare the validity and effectiveness of 2 methods for expanding depth of focus to correct for presbyopia; that is, induction of spherical aberration and small-pupil apertures.
SETTING: University of California, Berkeley, California, USA.
DESIGN: Comparative case series.
METHODS: A random 4-alternative forced-choice acuity task was performed on 13 subjects. Visual performance and depth of focus were compared using adaptive optics-corrected distance visual acuity (CDVA) values and mean visual acuity over a 3.0 diopter (D) range of defocus using the following 3 adaptive optics-corrected profiles: 2.0 mm pupil, 5.0 mm pupil, and 5.0 mm pupil with -0.274 μm of spherical aberration.
RESULTS: The 5.0 mm pupil profile had a CDVA of -0.218 logMAR and a mean visual acuity through focus of 0.156 logMAR. The 2.0 mm pupil profile had a worse CDVA (0.012 logMAR) but an improved mean visual acuity (0.061 logMAR). The 5.0 mm pupil profile with -0.274 μm of spherical aberration measured a CDVA of -0.082 logMAR and a mean visual acuity of 0.103 logMAR.
CONCLUSIONS: The spherical aberration and small-pupil profiles improved the mean visual acuity across a 3.0 D range of defocus but resulted in decreased CDVA at the plane of best focus in comparison to an adaptive optics-corrected 5.0 mm pupil. Small-pupil profiles are a better choice than spherical aberration profiles for presbyopic corrections due to expected accuracy, predictability, and patient satisfaction.
FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.
Adam Hickenbotham; Pavan Tiruveedhula; Austin Roorda
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural     Date:  2012-09-30
Journal Detail:
Title:  Journal of cataract and refractive surgery     Volume:  38     ISSN:  1873-4502     ISO Abbreviation:  J Cataract Refract Surg     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-30     Completed Date:  2013-03-20     Revised Date:  2013-12-04    
Medline Journal Info:
Nlm Unique ID:  8604171     Medline TA:  J Cataract Refract Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2071-9     Citation Subset:  IM    
Copyright Information:
Published by Elsevier Inc.
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MeSH Terms
Cornea / physiopathology*
Corneal Wavefront Aberration / physiopathology*
Depth Perception / physiology*
Mydriatics / administration & dosage
Presbyopia / physiopathology*
Pupil / drug effects,  physiology*
Treatment Outcome
Visual Acuity / physiology*
Grant Support
K12 EY017269/EY/NEI NIH HHS; L30 EY019175/EY/NEI NIH HHS
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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