| Comparison of special interest computed tomography, endosonography and histopathological stage of oesophageal cancer. | |
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MedLine Citation:
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PMID: 15145719 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: To assess the strength of agreement between the perceived pre-operative stage of oesophageal tumours as determined by spiral computed tomography (CT) and endoscopic ultrasound (EUS), both alone and in combination, with the histopathological stage. METHODS: Sixty patients with oesophageal cancer underwent both pre-operative CT and EUS performed by two consultant radiologists with a special interest in upper gastrointestinal radiology. The strength of the agreement between the radiological stage and the histopathological stage was determined by means of the weighted Kappa statistic (Kw). RESULTS: Sensitivity for T and N stages was 58% and 79% for CT, and 72% and 91% for EUS. Specificity for T and N stages was 80% and 84% for CT, and 85% and 68% for EUS. Kw for T and N stages was 0.455 (p=0.0001) and 0.603 (p=0.0001) for CT compared with 0.604 (p=0.0001) and 0.610 (p=0.0001) for EUS. In patients when CT and EUS agreed regarding the T and N stages, the strength of agreement between the radiological and the histopathological stage was greater (Kw T 0.613 (p=0.0001), Kw N 0.781 (p=0.0001)). CONCLUSION: CT and EUS are complimentary techniques for the staging of oesophageal tumours, and these results reinforce the importance of specialist radiology in stage directed management. |
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Authors:
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S R Weaver; G R J C Blackshaw; W G Lewis; P Edwards; S A Roberts; G V Thomas; M C Allison |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Clinical radiology Volume: 59 ISSN: 0009-9260 ISO Abbreviation: Clin Radiol Publication Date: 2004 Jun |
Date Detail:
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Created Date: 2004-05-17 Completed Date: 2004-07-19 Revised Date: 2010-03-23 |
Medline Journal Info:
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Nlm Unique ID: 1306016 Medline TA: Clin Radiol Country: England |
Other Details:
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Languages: eng Pagination: 499-504 Citation Subset: IM |
Affiliation:
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Department of Surgery, Royal Gwent Hospital, Newport, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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pathology*,
radiography,
ultrasonography Adult Aged Carcinoma, Squamous Cell / pathology*, radiography, ultrastructure Endosonography* / methods Esophageal Neoplasms / pathology*, radiography, ultrasonography Female Humans Lymphatic Metastasis Male Middle Aged Neoplasm Staging / methods*, standards Prospective Studies Sensitivity and Specificity Tomography, X-Ray Computed* / methods |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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