Document Detail


Comparison of slow oscillating versus fast balloon inflation strategies for coronary angioplasty.
MedLine Citation:
PMID:  10080417     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Previous studies suggest that slow and/or oscillating balloon inflation during coronary angioplasty may decrease the incidence of coronary dissection and improve clinical outcomes. To compare the effect of slow oscillating versus conventional fast inflation techniques on the incidence of severe coronary dissection during angioplasty, 622 patients were randomized to slow oscillating inflation versus fast inflation. Angiographic outcomes of the procedures and in-hospital clinical events were recorded. The primary end point of severe (type C, D, E, F) dissection occurred in 7.7% of patients undergoing slow oscillation and 6.6% of patients undergoing fast inflation (p = 0.87). Major complications (death, urgent coronary artery bypass graft surgery, stroke, abrupt closure, or Q-wave myocardial infarction) occurred in 4.7% of patients undergoing slow oscillation and 3.5% of patients undergoing fast inflation (p = 0.45). The 2 inflation strategies did not differ in the pressure at which the balloon achieved full expansion, angiographic success rate, residual stenosis, and incidence of all minor and/or major complications. We conclude that there is no benefit of slow oscillating inflation over routine fast inflation in angioplasty. Slow oscillating inflation did not dilate lesions at lower pressures, decrease the incidence of dissection or severe dissection, or reduce the incidence of adverse clinical outcomes.
Authors:
J C Blankenship; M W Krucoff; S W Werns; H V Anderson; C Landau; H J White; C L Green; A M Spokojny; R G Bach; R E Raymond; J Pinkston; M Rawert; J D Talley
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of cardiology     Volume:  83     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-04-01     Completed Date:  1999-04-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  675-80     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiology, Geisinger Medical Center, Penn State Geisinger Health System, Danville 17822, USA. jblankenship@PSGH5.edu
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MeSH Terms
Descriptor/Qualifier:
Aged
Aneurysm, Dissecting / prevention & control
Angioplasty, Transluminal, Percutaneous Coronary / adverse effects,  instrumentation,  methods*
Cerebrovascular Disorders / etiology
Cineradiography
Coronary Angiography
Coronary Artery Bypass
Coronary Disease / physiopathology,  therapy*
Coronary Vessels / pathology
Electrocardiography
Female
Humans
Incidence
Male
Middle Aged
Myocardial Infarction / etiology
Recurrence
Survival Rate
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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