| Comparison of slide coagglutination test and countercurrent immunoelectrophoresis for detection of group B streptococcal antigen in cerebrospinal fluid from infants with meningitis. | |
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MedLine Citation:
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PMID: 6991524 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The usefulness of Phadebact streptococcus reagents for the detection of group B streptococcal antigen in cerebrospinal fluid was evaluated in 54 infants with meningitis and in 22 normal infants. Antigens was detected by slide coagglutination in 19 (82.6%) and by countercurrent immunoelectrophoresis in 20 (87.0%) of 23 cerebrospinal fluid specimens from infants with group B streptococcal meningitis at admission. After initiation of antimicrobial therapy, antigen could be detected in 11 of 19 (by slide coagglutination) and 7 of 18 (by countercurrent immunoelectrophoresis) cerebrospinal fluids. False-positive reactions were noted by slide coagglutination in one infant with S. bovis meningitis and one with group B streptococcal bacteremia without meningitis; none occurred with countercurrent immunoelectrophoresis. The commercial availiability, simplicity, sensitivity (82.6%), and specificity (96.4%) of the Phadebact slide coaggluatination test for detecting group B streptococcal antigen in cerebrospinal fluid suggest that it may be useful for the early and rapid diagnosis of group B streptococcal meningitis. |
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Authors:
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B J Webb; M S Edwards; C J Baker |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of clinical microbiology Volume: 11 ISSN: 0095-1137 ISO Abbreviation: J. Clin. Microbiol. Publication Date: 1980 Mar |
Date Detail:
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Created Date: 1980-08-25 Completed Date: 1980-08-25 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 7505564 Medline TA: J Clin Microbiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 263-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Agglutination Tests* Antigens, Bacterial / analysis* Cerebrospinal Fluid / immunology* Counterimmunoelectrophoresis* Humans Immunoelectrophoresis* Infant Meningitis / diagnosis* Streptococcal Infections / diagnosis* Streptococcus agalactiae / immunology* |
| Chemical | |
Reg. No./Substance:
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0/Antigens, Bacterial |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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