Document Detail


Comparison of single dose netilmicin with a five-day course of co-trimoxazole for uncomplicated urinary tract infections.
MedLine Citation:
PMID:  6374533     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Women with uncomplicated urinary tract infections were randomly allocated to either a single 150 mg intramuscular dose of netilmicin or a standard five-day course of oral co-trimoxazole. Twenty-one of 22 were cured with netilmicin and all 20 with co-trimoxazole. No patient treated with netilmicin developed any side effects or obvious toxicity. Following co-trimoxazole one woman developed a severe skin rash and another nausea. Netilmicin is another drug which is highly effective when used in a single dose regimen for the treatment of uncomplicated urinary tract infections. There are many advantages of this approach to the management of a common clinical problem.
Authors:
R R Bailey; E Blake; B A Peddie
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The New Zealand medical journal     Volume:  97     ISSN:  0028-8446     ISO Abbreviation:  N. Z. Med. J.     Publication Date:  1984 Apr 
Date Detail:
Created Date:  1984-07-09     Completed Date:  1984-07-09     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0401067     Medline TA:  N Z Med J     Country:  NEW ZEALAND    
Other Details:
Languages:  eng     Pagination:  262-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Adolescent
Adult
Clinical Trials as Topic
Drug Combinations / administration & dosage
Escherichia coli Infections / drug therapy
Female
Gentamicins / administration & dosage*
Humans
Injections, Intramuscular
Middle Aged
Netilmicin / administration & dosage*
Prospective Studies
Random Allocation
Staphylococcal Infections / drug therapy
Sulfamethoxazole / administration & dosage*
Trimethoprim / administration & dosage*
Trimethoprim-Sulfamethoxazole Combination
Urinary Tract Infections / drug therapy*,  etiology
Chemical
Reg. No./Substance:
0/Drug Combinations; 0/Gentamicins; 56391-56-1/Netilmicin; 723-46-6/Sulfamethoxazole; 738-70-5/Trimethoprim; 8064-90-2/Trimethoprim-Sulfamethoxazole Combination

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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