| Comparison of single-breath vital capacity rapid inhalation with sevoflurane 5% and propofol induction on QT interval and haemodynamics for laparoscopic surgery. | |
| | |
MedLine Citation:
|
PMID: 15318466 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND AND OBJECTIVE: To compare two techniques to achieve induction of anaesthesia for laparoscopic surgery. A single-breath vital capacity rapid inhalation induction with sevoflurane was compared to intravenous propofol. Their effects on haemodynamics and the QT interval of the electrocardiogram were assessed. METHODS: Forty-four ASA I-II patients scheduled to undergo elective laparoscopic gynaecological surgery were divided into two groups. In the sevoflurane group (Group S, n = 22), general anaesthesia was induced with a single-breath vital capacity rapid inhalation of sevoflurane 5% with nitrous oxide (N2O) 65% in O2 and then anaesthesia was maintained with sevoflurane 1-1.5% with N2O 65% in O2. In the propofol group (Group P, n = 22), general anaesthesia was induced with propofol 2 mg kg(-1) intravenously and maintained with propofol 6 mg kg(-1) h(-1). Systolic, diastolic and mean arterial pressures, heart rate and end-tidal CO2 values were recorded before anaesthesia (basic value), during the induction period (time X), at 10 min (time Y) and at 30 min (time Z) of CO2 insufflation in all patients. QT intervals were calculated using Bazett's equation. RESULTS: Systolic, diastolic and mean arterial pressure values during the induction period (time X) were lower than the basic value in both groups (P < 0.05). In Group S, QTc intervals were significantly longer during the induction period (time X) and at the tenth min of CO2 insufflation (time Y) than Group P (P < 0.05). Five patients at time X and two patients at time Y developed ventricular dysrhythmias, which improved spontaneously in Group S. In Group P, there was no significant difference in QTc intervals and only one patient developed a ventricular dysrhythmia at time Y. CONCLUSIONS: Single-breath vital capacity rapid inhalation induction technique with sevoflurane can cause prolongation of the QT interval and dysrhythmias, compared with induction and maintenance of anaesthesia with propofol in laparoscopic surgery. |
| | |
Authors:
|
S Sen; G Ozmert; N Boran; H Turan; E Caliskan |
Related Documents
:
|
241366 - The effect of diazepam, flunitrazepam and droperidol with an analgesic on blood pressur... 11217886 - Increase in pulse transit time to the foot after epidural anaesthesia treatment. 7887116 - Circulatory drugs modify the hemodynamic actions of alfentanil combined with vecuronium... 11531666 - Exploration of xenon as a potential cardiostable sedative: a comparison with propofol a... 7086066 - Effects of ketamine and althesin anesthesia on baroreceptor--heart rate reflex and hemo... 2354316 - Effect of bladder filling on upper tract urodynamics in man. |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
|
Title: European journal of anaesthesiology Volume: 21 ISSN: 0265-0215 ISO Abbreviation: Eur J Anaesthesiol Publication Date: 2004 Jul |
Date Detail:
|
Created Date: 2004-08-20 Completed Date: 2004-11-09 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8411711 Medline TA: Eur J Anaesthesiol Country: England |
Other Details:
|
Languages: eng Pagination: 543-6 Citation Subset: IM |
Affiliation:
|
Adnan Menderes University, Department of Anesthesiology, Aydin, Turkey. uzmdrsenselda@mynet.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Anesthesia, General* Anesthetics, Inhalation / administration & dosage*, pharmacology Anesthetics, Intravenous / pharmacology* Blood Pressure / drug effects* Electrocardiography / drug effects* Female Gynecologic Surgical Procedures Heart Rate / drug effects* Humans Laparoscopy* Methyl Ethers / administration & dosage*, pharmacology Propofol / pharmacology* Vital Capacity* |
| Chemical | |
Reg. No./Substance:
|
0/Anesthetics, Inhalation; 0/Anesthetics, Intravenous; 0/Methyl Ethers; 2078-54-8/Propofol; 28523-86-6/sevoflurane |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effects of fentanyl on the incidence of emergence agitation in children receiving desflurane or sevo...
Next Document: Comparison of cuff-pressure changes in LMA-Classic and the new Soft Seal laryngeal masks during nitr...