Document Detail

Comparison of simultaneously performed digital and film-based angiography in assessment of coronary artery disease.
MedLine Citation:
PMID:  3191595     Owner:  NLM     Status:  MEDLINE    
This study compared digital angiography (Digital) to conventional cineangiography (Cine) for the diagnosis and quantification of coronary artery disease. Digital and Cine were obtained simultaneously under identical radiographic conditions during routine coronary arteriography. Using visual inspection and manual calipers, four independent observers identified 131 stenoses in 18 patients with multivessel coronary disease. There was no difference in interobserver variability between Digital and Cine during multiple subgroup analyses. Overall, Digital yielded significantly greater estimates of stenosis severity than did either of two separate Cine observations (p less than 0.0001; average difference, 6.25%), but the differences fell below the level of statistical significance when only the group of stenoses 50% or greater were considered. Digital and Cine correlated well for the assessment of stenosis severity (r = 0.88), but linear regression comparisons of multiple subgroups consistently indicated modest overestimation of Cine by Digital. Smaller vessels, branch vessels, and mild lesions increased the likelihood of overestimation by Digital. Digital was highly sensitive for identification of clinically relevant stenoses, but less specific and less predictive than a second observation of Cine. Our results indicate that Digital and Cine are not interchangeable imaging techniques and that potential differences must be considered when Digital is used for clinical decision making.
J C Gurley; S E Nissen; D C Booth; M Harrison; P Grayburn; J L Elion; A N DeMaria
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Circulation     Volume:  78     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1988 Dec 
Date Detail:
Created Date:  1989-01-12     Completed Date:  1989-01-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1411-20     Citation Subset:  AIM; IM    
Division of Cardiovascular Medicine, University of Kentucky Medical Center, Lexington.
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MeSH Terms
Angiography / methods*
Constriction, Pathologic / radiography
Coronary Disease / radiography*
Image Processing, Computer-Assisted*
Radiographic Image Enhancement

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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