Document Detail

Comparison of setup accuracy and intrafraction motion using stereotactic frame versus 3-point thermoplastic mask-based immobilization for fractionated cranial image guided radiation therapy.
MedLine Citation:
PMID:  24674361     Owner:  NLM     Status:  In-Data-Review    
PURPOSE: Prospectively compare patient setup accuracy and intrafraction motion of a standard 3-point thermoplastic mask with the Gill-Thomas-Cosman relocatable stereotactic frame, during fractionated cranial radiation therapy using the ExacTrac system (Brainlab AG Feldkirchen, Germany) for daily online correction.
METHODS AND MATERIALS: The number of fractions with all postcorrection and post-treatment errors <2 mm was assessed in 21 patients undergoing fractionated stereotactic radiation therapy (13 frame setup, 8 mask setup) using daily online correction. Achievable patient setup accuracy and total intrafraction motion were evaluated. The relative contributions of movement during floor rotation and patient movement to intrafraction motion were calculated.
RESULTS: With daily online correction, patient setup margins can be reduced from 1, 5, and 4 mm in the lateral, longitudinal, and vertical axes for mask setup and from 1-2, 2, and 1 mm, respectively, for frame setup to <1 mm isotropically for either immobilization system. Intrafraction movement was small for frame setup (mean [SD], -0.3 [0.3], -1.1[0.4], and -0.2 [0.6] in lateral, longitudinal and vertical axes, respectively; maximum, -2.7 mm [longitudinal axis]), and mask-setup (mean [SD], -0.4 [0.5], -0.8 [0.7], and 0.0 [0.3], respectively; maximum, -2.0 mm [longitudinal axis]) and is mainly due to floor rotation. Postcorrection and post-treatment errors were all <2 mm in 95% and 99% of fractions in the mask and frame, respectively, meeting the criteria for a 3-mm clinical target volume-planning target volume margin for either immobilization method.
CONCLUSIONS: Daily online correction can compensate for less precise immobilization and permits stereotactic margins to be used for standard thermoplastic masks without the need for specialized mask systems.
Nicola Abigail Rosenfelder; Lee Corsini; Helen McNair; Kjell Pennert; Alexandra Aitken; Caroline Mary Lamb; Michelle Long; Enrico Clarke; Mauricio Murcia; Ulrike Schick; Kevin Burke; Sue Ashley; Vincent Khoo; Michael Brada
Publication Detail:
Type:  Journal Article     Date:  2012-07-19
Journal Detail:
Title:  Practical radiation oncology     Volume:  3     ISSN:  1879-8500     ISO Abbreviation:  Pract Radiat Oncol     Publication Date:    2013 Jul-Sep
Date Detail:
Created Date:  2014-03-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101558279     Medline TA:  Pract Radiat Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  171-9     Citation Subset:  -    
Copyright Information:
Copyright © 2013 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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