| Comparison of serum progesterone as an indicator of pregnancy nonviability in spontaneously pregnant emergency room and infertility clinic patient populations. | |
MedLine Citation:
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PMID: 10689002 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To compare the predictive value of serum progesterone in identifying nonviable pregnancy in symptomatic spontaneously pregnant emergency department patients and asymptomatic patients attending an infertility clinic. DESIGN: Retrospective study. SETTING: Tertiary-care academic health center. PATIENT(S): One hundred thirty-seven pregnant patients who presented to the emergency department for whom clinical outcomes were available, and 123 consecutive patients who became pregnant during treatment at the infertility clinic. INTERVENTION(S): Serum progesterone measurement. MAIN OUTCOME MEASURE(S): The sensitivity, specificity, and predictive value of serum progesterone <45 nmol/L in identifying nonviable pregnancies were determined for each of the groups. RESULT(S): Sensitivity and specificity of serum progesterone <45 nmol/L in predicting nonviable pregnancies were 88.6% and 87.5%, respectively, in spontaneously pregnant patients who presented to the emergency department with pain or bleeding and 58.8% and 100% in infertility patients who had undergone controlled ovarian hyperstimulation for in vitro fertilization or intrauterine insemination. Sensitivity and specificity for all other infertility clinic patients were variable. CONCLUSION(S): The predictive value of low serum progesterone in identifying nonviable pregnancies varies with patient populations. |
Authors:
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S L Perkins; M Al-Ramahi; P Claman |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 73 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 2000 Mar |
Date Detail:
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Created Date: 2000-03-23 Completed Date: 2000-03-23 Revised Date: 2014-07-28 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 499-504 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Spontaneous
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epidemiology Algorithms False Positive Reactions Female Fetal Death / diagnosis*, epidemiology Humans Infertility, Female / therapy Ovulation Induction Predictive Value of Tests Pregnancy Pregnancy, Ectopic / epidemiology Progesterone / blood* Retrospective Studies Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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4G7DS2Q64Y/Progesterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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