Document Detail

Comparison of serum progesterone as an indicator of pregnancy nonviability in spontaneously pregnant emergency room and infertility clinic patient populations.
MedLine Citation:
PMID:  10689002     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the predictive value of serum progesterone in identifying nonviable pregnancy in symptomatic spontaneously pregnant emergency department patients and asymptomatic patients attending an infertility clinic.
DESIGN: Retrospective study.
SETTING: Tertiary-care academic health center.
PATIENT(S): One hundred thirty-seven pregnant patients who presented to the emergency department for whom clinical outcomes were available, and 123 consecutive patients who became pregnant during treatment at the infertility clinic.
INTERVENTION(S): Serum progesterone measurement.
MAIN OUTCOME MEASURE(S): The sensitivity, specificity, and predictive value of serum progesterone <45 nmol/L in identifying nonviable pregnancies were determined for each of the groups.
RESULT(S): Sensitivity and specificity of serum progesterone <45 nmol/L in predicting nonviable pregnancies were 88.6% and 87.5%, respectively, in spontaneously pregnant patients who presented to the emergency department with pain or bleeding and 58.8% and 100% in infertility patients who had undergone controlled ovarian hyperstimulation for in vitro fertilization or intrauterine insemination. Sensitivity and specificity for all other infertility clinic patients were variable.
CONCLUSION(S): The predictive value of low serum progesterone in identifying nonviable pregnancies varies with patient populations.
S L Perkins; M Al-Ramahi; P Claman
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  73     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-03-23     Completed Date:  2000-03-23     Revised Date:  2014-07-28    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  499-504     Citation Subset:  IM    
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MeSH Terms
Abortion, Spontaneous / epidemiology
False Positive Reactions
Fetal Death / diagnosis*,  epidemiology
Infertility, Female / therapy
Ovulation Induction
Predictive Value of Tests
Pregnancy, Ectopic / epidemiology
Progesterone / blood*
Retrospective Studies
Sensitivity and Specificity
Reg. No./Substance:

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