Document Detail

Comparison of secondary signs as shown by unenhanced helical computed tomography in patients with uric acid or calcium ureteral stones.
MedLine Citation:
PMID:  22632887     Owner:  NLM     Status:  MEDLINE    
Unenhanced helical computed tomography (UHCT) has evolved into a well-accepted diagnostic method in patients with suspected ureterolithiasis. UHCT not only shows stones within the lumen of the ureter, it also permits evaluation of the secondary signs associated with ureteral obstruction from stones. However, there we could find no data on how secondary signs might differ in relation to different compositions of ureteral stones. In this study, we compared the degree of secondary signs revealed by UHCT in uric acid stone formers and in patients forming calcium stones. We enrolled 117 patients with ureteral stones who underwent UHCT examination and Fourier transform infra-red analysis of stone samples. Clinical data were collected as follows: age, sex, estimated glomerular filtration rate (eGFR), urine pH, and radiological data on secondary signs apparent on UHCT. The uric acid stone formers had significantly lower urine pH and eGFR in comparison to calcium stone formers, and on UHCT they also had a higher percentage of the secondary signs, including rim sign (78.9% vs. 60.2%), hydroureter (94.7% vs. 89.8%), perirenal stranding (84.2% vs. 59.2%) and kidney density difference (73.7% vs. 50.0%). The radiological difference was statistically significant for perirenal stranding (p=0.041). In conclusion, we found that UHCT scanning reveals secondary signs to be more frequent in patients with uric acid ureteral stones than in patients with calcium stones, a tendency that might result from an acidic urine environment.
Yii-Her Chou; Wei-Po Chou; Mu-En Liu; Wei-Ming Li; Ching-Chia Li; Chia-Chu Liu; Yung-Shun Juan; Shu-Ching Pan
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Publication Detail:
Type:  Journal Article     Date:  2012-04-18
Journal Detail:
Title:  The Kaohsiung journal of medical sciences     Volume:  28     ISSN:  1607-551X     ISO Abbreviation:  Kaohsiung J. Med. Sci.     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-28     Completed Date:  2012-09-21     Revised Date:  2014-02-14    
Medline Journal Info:
Nlm Unique ID:  100960562     Medline TA:  Kaohsiung J Med Sci     Country:  China (Republic : 1949- )    
Other Details:
Languages:  eng     Pagination:  322-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2012. Published by Elsevier B.V.
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MeSH Terms
Aged, 80 and over
Calcium / chemistry*
Glomerular Filtration Rate / physiology*
Hydrogen-Ion Concentration
Middle Aged
Tomography, Spiral Computed / methods*
Ureteral Calculi / physiopathology*,  radiography*,  urine
Uric Acid / chemistry*
Young Adult
Reg. No./Substance:
268B43MJ25/Uric Acid; SY7Q814VUP/Calcium
Comment In:
Kaohsiung J Med Sci. 2014 Jan;30(1):52   [PMID:  24388059 ]

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