Document Detail

Comparison and reliability of two non-invasive acetylene uptake techniques for the measurement of cardiac output.
MedLine Citation:
PMID:  15918060     Owner:  NLM     Status:  MEDLINE    
Comparison and reliability of two non-invasive acetylene uptake techniques for the measurement of cardiac output. Thirteen trained male cyclists performed CO2 rebreathing (CO2RB) at intensities from rest to 200 W, and open-circuit acetylene uptake (OpCirc) and single-breath acetylene uptake (SB) at intensities from rest to 300 W, with all procedures using 50 W increments. Oxygen consumption VO2 cardiac output Q and heart rate (HR), were measured at each stage, and the values for each variable were compared within each intensity to determine reliability of the measuring device. Both the OpCirc and SBs were shown to be reliable measures of cardiac output (r = 0.95 and 0.92, respectively) with decreasing coefficients of variation (CV) as intensity increased, and were similar to published data. The Q-VO2 relationship using the SB diverged from the regression line for OpCirc and CO2RB. Linear regression of the Q--VO2 relationship for CO2RB was y = 6.18 x VO2 + 2.59 for OpCirc was y = 6.12 x VO2 + 2.98 and for SB was y = 5.05 x VO2 + 3.76. The OpCirc and SBs were both shown to be reliable techniques for measuring cardiac output, comparable to previously reported cardiac output measurements, and suitable for use in exercise testing. However, the SB, requiring a constant, slow exhalation rate, made the procedure difficult to perform at higher exercise intensities.
D W Dibski; D J Smith; R Jensen; S R Norris; G T Ford
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2005-05-26
Journal Detail:
Title:  European journal of applied physiology     Volume:  94     ISSN:  1439-6319     ISO Abbreviation:  Eur. J. Appl. Physiol.     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-07-26     Completed Date:  2005-10-20     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  100954790     Medline TA:  Eur J Appl Physiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  670-80     Citation Subset:  IM    
Faculty of Kinesiology, University of Calgary, 2500 University Drive, NW Calgary, AB, T2N1N4, Canada.
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MeSH Terms
Acetylene / administration & dosage*,  diagnostic use*
Administration, Inhalation
Cardiac Output / physiology*
Heart Function Tests / methods
Oxygen Consumption / physiology*
Physical Exertion / physiology*
Pulmonary Gas Exchange / physiology*
Reproducibility of Results
Sensitivity and Specificity
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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