Document Detail

Comparison and relation of indirect and direct dynamic indexes of cardiac pumping capacity in chronic heart failure.
MedLine Citation:
PMID:  16214454     Owner:  NLM     Status:  MEDLINE    
Cardiac power output (CPO), the product of cardiac output (CO) and mean arterial pressure (MAP), is a direct measure of cardiac pumping capability and is strongly indicative of prognosis and exercise ability in patients with chronic heart failure (CHF). However, it is not as easily measured as indirect indicators of cardiac function, such as peak oxygen consumption (VO(2)) or peak "circulatory power" (CircP), the product of VO(2) and MAP. The relation between direct and indirect indexes of cardiac pumping capacity was evaluated in 219 ambulatory patients with CHF. CircP was found to have a direct and consistent relation with CPO, overall (R = 0.93, p <0.0001) and at peak exercise (R = 0.84, p < 0.0001). The results suggest CircP to be an adequate measure of cardiac pumping capacity when the more directly measured CPO is not available.
Simon G Williams; Bing-H Tzeng; Diane Barker; Lip-Bun Tan
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article     Date:  2005-09-01
Journal Detail:
Title:  The American journal of cardiology     Volume:  96     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-10-10     Completed Date:  2005-11-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1149-50     Citation Subset:  AIM; IM    
Cardiac Transplant Unit, Wythenshawe Hospital, Wythenshawe, Manchester, UK.
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MeSH Terms
Cardiac Output*
Chronic Disease
Heart Failure / physiopathology*
Middle Aged
Oxygen Consumption*

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