Document Detail


Comparison of pulsatility indices on the day of oocyte retrieval and embryo transfer.
MedLine Citation:
PMID:  7745076     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Transvaginal ultrasonography with colour blood flow imaging and analysis of impedance to uterine arterial blood flow has been used to provide an index of uterine receptivity for implantation after IVF/embryo transfer. A mean uterine arterial pulsatility index (PI) > 3.0 at the time of embryo transfer predicted 35% of failures to become pregnant. Cryopreserving embryos in non-receptive cycles and transferring them in receptive cycles would be expected to improve pregnancy rates. Earlier decisions regarding embryo cryopreservation can be made if receptive cycles can be predicted at the time of oocyte retrieval rather than at embryo transfer. To assess differences in uterine artery impedance, PI were measured serially in 107 women on both the day of oocyte retrieval and the day of embryo transfer. Mean PI on the day of oocyte retrieval was 2.52 +/- 0.59, and on the day of embryo transfer was 2.78 +/- 0.45. No significant difference was observed when PI determined on the day of oocyte retrieval were compared with PI on the day of embryo transfer. These data suggest that the PI measurement done on the day of oocyte retrieval could substitute for the measurement done on the day of embryo transfer. This would allow prediction of non-receptive endometria earlier in the cycle. Further studies are needed to evaluate whether cryopreservation of embryos and transfer when the uterus is more receptive will increase the implantation rates.
Authors:
C B Coulam; J J Stern; D M Soenksen; S Britten; M Bustillo
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  10     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1995 Jan 
Date Detail:
Created Date:  1995-06-09     Completed Date:  1995-06-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  82-4     Citation Subset:  IM    
Affiliation:
Genetics & IVF Institute, Fairfax, VA 22031, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Cryopreservation
Embryo Transfer*
Female
Fertilization in Vitro
Humans
Oocytes
Pregnancy
Pulsatile Flow
Regional Blood Flow
Uterus / blood supply*,  ultrasonography
Vascular Resistance

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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