Document Detail

Comparison of pulmonary artery and aortic transpulmonary thermodilution for monitoring of cardiac output in patients with severe heart failure: validation of a novel method.
MedLine Citation:
PMID:  19050622     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Hemodynamic monitoring with the pulmonary artery catheter is frequently used in the management of severe heart failure. For measurement of cardiac output (CO), transpulmonary thermodilution (TPTD) has recently been adopted into clinical practice as an alternative to pulmonary artery thermodilution. However, no data have been published on the comparability of the two methods for patients with severely reduced left ventricular function. Our objective was to evaluate the correlation between these two methods of CO determination in patients with severe left ventricular dysfunction. DESIGN: Prospective observational clinical study. SETTING: Cardiological intermediate care unit and medical intensive care unit of a university hospital. PATIENTS: Twenty-nine patients with left ventricular ejection fraction <35% and symptoms of heart failure (New York Heart Association class III-IV). INTERVENTION: None. MEASUREMENTS AND MAIN RESULTS: The two methods of intermittent CO measurement were compared by simultaneously recording the results of pulmonary artery thermodilution and TPTD after injection of a cold saline bolus. Measurements were performed when clinically necessary. A total of 325 data pairs were analyzed. Mean CO of both methods was 4.4 L/min with a bias of 0.45 L/min (2 SD 1.20 L/min), resulting in a percentage error of 27.3%. CONCLUSION: In patients with severely impaired left ventricular function, measurement of CO by TPTD provides valid results.
Sigrun Friesecke; Annegret Heinrich; Peter Abel; Stephan B Felix
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Validation Studies    
Journal Detail:
Title:  Critical care medicine     Volume:  37     ISSN:  1530-0293     ISO Abbreviation:  Crit. Care Med.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-31     Completed Date:  2009-02-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  119-23     Citation Subset:  AIM; IM    
Department of Internal Medicine B, Division of Cardiology, Pneumology, and Critical Care Medicine, University of Greifswald, Greifswald, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aorta, Thoracic*
Cardiac Output*
Heart Failure / physiopathology*
Middle Aged
Monitoring, Physiologic
Prospective Studies
Pulmonary Artery*
Severity of Illness Index
Thermodilution / methods*
Ventricular Dysfunction, Left / physiopathology*
Comment In:
Crit Care Med. 2009 Jan;37(1):343-4   [PMID:  19112295 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Racial and ethnic disparities in mortality from acute lung injury.
Next Document:  The potential mechanisms of reduced incidence of ventricular fibrillation as the presenting rhythm i...