Document Detail


Comparison of proton and x-ray conformal dose distributions for radiosurgery applications.
MedLine Citation:
PMID:  8746720     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Highly focused dose distributions for radiosurgery applications are successfully achieved using either multiple static high-energy particle beams or multiple-arc circular x-ray beams from a linac. It has been suggested that conformal x-ray techniques using dynamically shaped beams with a moving radiation source would offer advantages compared to the use of only circular beams. It is also thought that, generally, charged particle beams such as protons offer dose deposition advantages compared to x-ray beams. A comparison of dose distributions was made between a small number of discrete proton beams, multiple-arc circular x-ray beams, and conformal x-ray techniques. Treatment planning of a selection of radiosurgery cases was done for these three techniques. Target volumes ranged from 1.0-25.0 cm3. Dose distributions and dose volume histograms of the target and surrounding normal brain were calculated. The advantages and limitations of each technique were primarily dependent upon the shape and size of the target volume. In general, proton dose distributions were superior to x-ray distributions; both shaped proton and shaped x-ray beams delivered dose distributions which were more conformal than x-ray techniques using circular beams; and the differences between all proton and x-ray distributions were negligible for the smallest target volumes, and greatest for the larger target volumes.
Authors:
C F Serago; A F Thornton; M M Urie; P Chapman; L Verhey; S J Rosenthal; K P Gall; A Niemierko
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Medical physics     Volume:  22     ISSN:  0094-2405     ISO Abbreviation:  Med Phys     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1996-10-24     Completed Date:  1996-10-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0425746     Medline TA:  Med Phys     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2111-6     Citation Subset:  IM    
Affiliation:
Massachusetts General Hospital, Harvard Medical School, Department of Radiation Oncology, Boston 02114, USA.
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MeSH Terms
Descriptor/Qualifier:
Biophysical Phenomena
Biophysics
Humans
Protons
Radiosurgery* / statistics & numerical data
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted* / statistics & numerical data
Technology, Radiologic
X-Rays
Chemical
Reg. No./Substance:
0/Protons

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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