Document Detail


Comparison of propranolol, sotalol, and betaxolol in the treatment of neuroleptic-induced akathisia.
MedLine Citation:
PMID:  2884889     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In earlier open studies, beta-blockers were found to be effective in the treatment of neuroleptic-induced akathisia. In the present study, 16 patients with severe neuroleptic-induced akathisia successively received low doses of three beta-blockers--propranolol, sotalol, and betaxolol. There was rapid and complete improvement in seven of 16 patients (and partial improvement in three patients) treated with betaxolol. The efficacy of propranolol and betaxolol and failure of sotalol in treating neuroleptic-induced akathisia suggest a central mechanism of action.
Authors:
B Dupuis; J Catteau; J P Dumon; C Libert; H Petit
Related Documents :
20958219 - Short and long term anti-inflammatory effects of bosentan therapy in patients with pulm...
2676169 - Hemodynamic and clinical effects of captopril in patients with severe congestive heart ...
17207719 - Influence of blood pressure on the effectiveness of a fixed-dose combination of isosorb...
7721419 - Comparison of effects of angiotensin i-converting enzyme inhibition and beta-blockade f...
15530189 - Postoperative fluid balance influences the need for antihypertensive therapy following ...
2663239 - Ketanserin in the treatment of essential hypertension. a double blind trial against met...
25132379 - Impact of eicosapentaenoic acid treatment on the fibrous cap thickness in patients with...
22207449 - Led (660 nm) and laser (670 nm) use on skin flap viability: angiogenesis and mast cel...
2128829 - Effectiveness of ketotifen in the treatment of neurodermatitis in childhood.
Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  The American journal of psychiatry     Volume:  144     ISSN:  0002-953X     ISO Abbreviation:  Am J Psychiatry     Publication Date:  1987 Jun 
Date Detail:
Created Date:  1987-07-01     Completed Date:  1987-07-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370512     Medline TA:  Am J Psychiatry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  802-5     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Akathisia, Drug-Induced
Antipsychotic Agents / adverse effects*
Betaxolol
Clinical Trials as Topic
Dose-Response Relationship, Drug
Female
Humans
Male
Middle Aged
Propanolamines / administration & dosage,  therapeutic use*
Propranolol / administration & dosage,  therapeutic use*
Psychomotor Agitation / drug therapy*
Sotalol / administration & dosage,  therapeutic use*
Chemical
Reg. No./Substance:
0/Antipsychotic Agents; 0/Propanolamines; 3930-20-9/Sotalol; 525-66-6/Propranolol; 63659-18-7/Betaxolol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Psychological and interpersonal issues in space.
Next Document:  Rapidly progressive hearing loss as a symptom of polyarteritis nodosa.