| Comparison of propofol with methohexitone in the provision of anaesthesia for surgery under regional blockade. | |
| | |
MedLine Citation:
|
PMID: 3878717 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Propofol was compared with methohexitone for provision of light general anaesthesia in patients undergoing surgery under spinal analgesia. Intermittent bolus administration of both agents proved a feasible way of maintaining anaesthesia, a mean infusion rate of 0.13 mg kg-1 min-1 being required for propofol and 0.089 mg kg-1 min-1 for methohexitone. Propofol produced smoother anaesthesia with significantly fewer excitatory side effects and less pain on injection, but cardiovascular and respiratory depression occurred commonly. Recovery was rapid with both agents, but minor postoperative sequelae occurred more frequently after methohexitone. |
| | |
Authors:
|
N Mackenzie; I S Grant |
Related Documents
:
|
7992907 - Hemodynamic response to induction and intubation. propofol/fentanyl interaction. 906217 - An evaluation of chemical restraining agents in the horse. 19121157 - Yohimbine antagonizes the anaesthetic effects of ketamine-xylazine in captive indian wi... 11573657 - Gender differences in the pharmacokinetics of propofol in elderly patients during and a... 14671427 - Correlation of meropenem plasma levels with pharmacodynamic requirements in critically ... 3943107 - Steady-state nonlinear pharmacokinetics of 5-fluorouracil during hepatic arterial and i... |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
|
Title: British journal of anaesthesia Volume: 57 ISSN: 0007-0912 ISO Abbreviation: Br J Anaesth Publication Date: 1985 Dec |
Date Detail:
|
Created Date: 1986-02-28 Completed Date: 1986-02-28 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0372541 Medline TA: Br J Anaesth Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 1167-72 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Anesthesia Recovery Period Anesthesia, Conduction* Anesthesia, Intravenous* Anesthetics* / pharmacology Humans Leg / surgery Methohexital* / pharmacology Middle Aged Phenols* / pharmacology Propofol Psychomotor Performance / drug effects Time Factors |
| Chemical | |
Reg. No./Substance:
|
0/Anesthetics; 0/Phenols; 18652-93-2/Methohexital; 2078-54-8/Propofol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Ro (SS-A) antibody and antigen in a patient with congenital complete heart block.
Next Document: Comparison of infusions of propofol and methohexitone to provide light general anaesthesia during su...