Document Detail

Comparison of propofol infusion and isoflurane for maintenance of anesthesia for dentistry in mentally retarded patients.
MedLine Citation:
PMID:  1308378     Owner:  NLM     Status:  MEDLINE    
A continuous infusion of propofol following an induction dose of 2 mg/kg was compared with thiopental/isoflurane for the induction and maintenance of anesthesia in 20 mentally retarded outpatients undergoing routine dental procedures. The infusion rate of propofol and the concentration of isoflurane were adjusted to maintain the heart rate and blood pressure within +/- 25% of the baseline values. Postoperative wakefulness was assessed using a 100-mm visual analogue scale at the time of extubation and at 5, 10, 15, 30, 60, 90, and 120 min after extubation. Both agents provided adequate anesthesia for the treatment, and no major adverse reactions occurred. Recovery was more complete during the first hour after extubation in the propofol group, and these patients were discharged earlier.
H Antila; J Valli; M Valtonen; J Kanto
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Anesthesia progress     Volume:  39     ISSN:  0003-3006     ISO Abbreviation:  Anesth Prog     Publication Date:  1992  
Date Detail:
Created Date:  1993-09-24     Completed Date:  1993-09-24     Revised Date:  2010-09-07    
Medline Journal Info:
Nlm Unique ID:  0043533     Medline TA:  Anesth Prog     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  83-6     Citation Subset:  D    
Department of Anesthesiology, Turku University Central Hospital, Finland.
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MeSH Terms
Analysis of Variance
Anesthesia Recovery Period
Anesthesia, Dental / methods*
Anesthesia, Inhalation
Blood Pressure / drug effects
Dental Care for Disabled / methods*
Diazepam / therapeutic use
Infusions, Intravenous
Mental Retardation*
Time Factors
Reg. No./Substance:
2078-54-8/Propofol; 26675-46-7/Isoflurane; 439-14-5/Diazepam

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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