Document Detail

Comparison of prevalence of >70% diameter narrowing of one or more major coronary arteries in patients with versus without mitral annular calcium and clinically suspected coronary artery disease.
MedLine Citation:
PMID:  18312759     Owner:  NLM     Status:  MEDLINE    
The prevalence of >70% narrowing of 1, 2, or 3 major coronary arteries and of 3 major coronary arteries was investigated in 2,465 patients (1,437 men, 1,028 women; mean age 69 +/- 13 years) with severe, moderate, mild, or no mitral annular calcium (MAC) diagnosed by 2-dimensional echocardiography who underwent coronary angiography for suspected coronary artery disease. Greater than 70% narrowing of 1, 2, or 3 major coronary arteries was present in 259 of 315 patients (82%) with severe MAC (group 1), in 835 of 1,052 patients (79%) with moderate or mild MAC (group 2), and in 756 of 1,098 patients (69%) with no MAC (group 3) (p <0.001 comparing group 1 with group 3 and group 2 with group 3). Greater than 70% narrowing of 3 major coronary arteries was present in 149 of 315 patients (47%) in group 1, in 366 of 1,052 patients (35%) in group 2, and in 325 of 1,098 patients (30%) in group 3 (p <0.001 comparing group 1 with group 3 and group 1 with group 2; p <0.01 comparing group 2 with group 3). In conclusion, MAC is associated with obstructive >or=1-vessel coronary artery disease and with obstructive 3-vessel coronary artery disease.
Hari Kannam; Wilbert S Aronow; Kiran Chilappa; Tarunjit Singh; John A McClung; Anthony L Pucillo; Melvin B Weiss; Kumar Kalapatapu; Thomas Sullivan; Craig E Monsen
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Publication Detail:
Type:  Journal Article     Date:  2007-12-20
Journal Detail:
Title:  The American journal of cardiology     Volume:  101     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-03-03     Completed Date:  2008-03-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  467-70     Citation Subset:  AIM; IM    
Department of Medicine, Cardiology Division, New York Medical College, Valhalla, New York, USA.
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MeSH Terms
Calcinosis / ultrasonography*
Coronary Angiography*
Coronary Artery Disease / radiography*
Heart Valve Diseases / ultrasonography*
Mitral Valve / ultrasonography*
Severity of Illness Index

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