| Comparison of preseasonal and coseasonal Allpyral with Depo-Medrone in summer hay-fever. | |
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MedLine Citation:
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PMID: 4883848 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Three hundred patients with grass pollen hay-fever, with or without pollen asthma, were given one of three forms of treatment: preseasonal or coseasonal alum-precipitated pyridine extracted grass pollen (Allpyral) or methylprednisolone acetate in slow-release form (Depo-Medrone). Significant improvement was obtained with preseasonal Allpyral and with Depo-Medrone, but the degree of improvement obtained with coseasonal Allpyral fell within the limits of placebo response.Nevertheless, it is considered that the definite suppression of the pituitary-adrenal function which results from the use of a long-term steroid is not justified in a benign condition such as hay-fever. |
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Authors:
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M A Ganderton; J Brostoff; A W Frankland |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: British medical journal Volume: 1 ISSN: 0007-1447 ISO Abbreviation: Br Med J Publication Date: 1969 Feb |
Date Detail:
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Created Date: 1969-03-05 Completed Date: 1969-03-05 Revised Date: 2012-05-07 |
Medline Journal Info:
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Nlm Unique ID: 0372673 Medline TA: Br Med J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 357-8 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Asthma
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drug therapy Clinical Trials as Topic Delayed-Action Preparations Humans Methylprednisolone / administration & dosage, therapeutic use Poaceae Pollen Pyridines / administration & dosage, adverse effects, therapeutic use Rhinitis, Allergic, Seasonal / drug therapy Seasons |
| Chemical | |
Reg. No./Substance:
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0/Delayed-Action Preparations; 0/Pyridines; 83-43-2/Methylprednisolone |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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