Document Detail

Comparison of post amputation outcome in patients with type 2 diabetes from specialized foot care centres in three developing countries.
MedLine Citation:
PMID:  20299119     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate post amputation outcome and associated complications in type 2 diabetic patients who had undergone major amputations in developing countries. PATIENTS AND METHODS: A total of 526 (M:F; 369:157) subjects from three centers [India (IND), n=194, Bangladesh (BAN) n=177 and Tanzania (TAN) n=155 who had undergone amputation and subsequently visited the hospital were included in this analysis. Details on foot problems and associated complications were recorded. RESULTS: The prevalence of amputations was similar in all centres. The history of minor amputation and foot deformity was high in BAN. Recurrence of foot ulceration was more in TAN (30%) than in IND (9%) and BAN (11%). Re-amputation rate was similar in all groups (3%). The use of artificial limb was most in BAN (97%). Myocardial infarction was more prevalent in IND (15%). In Tanzania, 31% had died during the follow-up period and it was 16% and 5% in IND and BAN. The causes of death were infection due to septicemia and cardiovascular events which finally led to multisystem organ failure. CONCLUSION: The outcome following a major diabetic foot amputation was compared in three developing countries. Recurrence of foot infection was common in Tanzania. The most frequent causes of death were infection and cardiovascular events.
Vijay Viswanathan; Jawadur Rahim Wadud; Sivagami Madhavan; Seena Rajasekar; Satyavani Kumpatla; J K Lutale; Zulfiqarali G Abbas
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study     Date:  2010-03-17
Journal Detail:
Title:  Diabetes research and clinical practice     Volume:  88     ISSN:  1872-8227     ISO Abbreviation:  Diabetes Res. Clin. Pract.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-26     Completed Date:  2010-08-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508335     Medline TA:  Diabetes Res Clin Pract     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  146-50     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Ireland Ltd. All rights reserved.
M.V. Hospital for Diabetes and Diabetes Research Centre, WHO Collaborating Centre for Research, Education &Training in Diabetes, Royapuram, Chennai, India.
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MeSH Terms
Bangladesh / epidemiology
Cardiovascular Diseases
Cause of Death
Developing Countries
Diabetes Mellitus, Type 2 / complications*
Diabetic Foot / epidemiology,  surgery*
India / epidemiology
Middle Aged
Tanzania / epidemiology
Treatment Outcome

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