| Comparison of positron emission tomography and lymphangiography in the diagnosis of infradiaphragmatic Hodgkin's disease. | |
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MedLine Citation:
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PMID: 17325926 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To evaluate the respective roles of positron emission tomography using 18F-fluorodeoxyglucose (FDG-PET) and lymphangiography (LAG) in staging Hodgkin's disease (HD) patients with negative contrast-enhanced infradiaphragmatic computed tomography (CT). MATERIAL AND METHODS: 28 patients underwent FDG-PET and LAG at initial staging. Concordant positive findings on both tests were regarded as actual HD locations and concordant negative findings as true negative. In case of discrepancy, the reference was biopsy or magnetic resonance imaging (MRI). RESULTS: Concordant results were obtained in 26 patients (24 negative, two positive). In two of the 24 negative patients, PET showed additional lesions in the spleen and one celiac lymph node (one patient), and in the right kidney and the right iliac crest (one patient). Discordant results were obtained in two patients. Both methods indicated infradiaphragmatic involvement in different locations in one patient. In the other, PET was falsely positive (PET done within 24 hours after a negative LAG), which was confirmed by biopsy (benign inflammatory, probably due to LAG medium). CONCLUSION: FDG-PET and LAG gave comparable results, making invasive LAG unnecessary. Furthermore, LAG, when performed before PET, can be responsible for false-positive PET results. |
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Authors:
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F Valette; S Querellou; A Oudoux; T Carlier; B Dupas; J-F Chatal; O Couturier |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article |
Journal Detail:
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Title: Acta radiologica (Stockholm, Sweden : 1987) Volume: 48 ISSN: 0284-1851 ISO Abbreviation: Acta Radiol Publication Date: 2007 Feb |
Date Detail:
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Created Date: 2007-02-27 Completed Date: 2007-03-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8706123 Medline TA: Acta Radiol Country: Sweden |
Other Details:
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Languages: eng Pagination: 59-63 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine and Department of Radiology, Hospital of the University of Nantes, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Diaphragm / radiography, radionuclide imaging Female Fluorodeoxyglucose F18 / diagnostic use Hodgkin Disease / diagnosis* Humans Kidney / radionuclide imaging Lymph Nodes / radionuclide imaging Lymphography / methods Male Middle Aged Neoplasm Staging / methods* Positron-Emission Tomography / methods* Radiopharmaceuticals / diagnostic use Reproducibility of Results Retrospective Studies Spleen / radionuclide imaging |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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