| Comparison of patients with anterior wall healed myocardial infarction with and without exercise-induced ST-segment elevation. | |
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MedLine Citation:
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PMID: 9462598 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To assess the extent of myocardial necrosis and ischemia in patients with anterior wall healed myocardial infarction depending on whether ST-segment elevation was present on precordial leads during exercise testing, 62 consecutive patients (49 men and 13 women, age [mean +/- SD] 56 +/- 11 years) with anterior wall infarcts were assessed with exercise technetium-99m (Tc-99m) methoxy-isobutyl-isonitrile single-photon emission computed tomography and quantification of the extent of necrosis and ischemia on polar maps: 22 patients had > or = 1 mm ST-segment elevation during exercise, and 40 did not. The extent of the necrosis in the anteroseptal (p = 0.001) and apical (p = 0.002) regions, the extent of ischemia in the lateral region (p = 0.003) on polar maps, and the frequency of ventricular aneurysm as shown by cardiac catheterization (p = 0.001) were significantly greater in patients with ST-segment elevation. In a multiple logistic regression model, both extent of necrosis in the anteroseptal region (odds ratio 10.8; 95% confidence interval 2.7 to 44.0) and extent of ischemia in the lateral region (odds ratio 7.25; 95% confidence interval 1.6 to 32.7) were associated with exercise-induced ST-segment elevation. These data suggest that ST-segment elevation in anterior infarctions is associated with wider necrosis in the anteroseptal and apical regions, with a wider extent of ischemia in the lateral region and a higher frequency of ventricular aneurysm. Consequently, it cannot be used as a marker of viability. |
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Authors:
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J Candell-Riera; C Santana-Boado; L Armadans-Gil; P Blanch; S Aguadé; J Castell; J Vaqué-Rafart; J Soler-Soler |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The American journal of cardiology Volume: 81 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1998 Jan |
Date Detail:
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Created Date: 1998-02-19 Completed Date: 1998-02-19 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 12-6 Citation Subset: AIM; IM |
Affiliation:
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Servei de Cardiologia, Hospital General Universitari Vall d'Hebron, Barcelona, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Contrast Media* Coronary Angiography Electrocardiography* / standards Exercise Test* / standards Female Heart Catheterization Humans Logistic Models Male Middle Aged Myocardial Infarction / classification, diagnosis* Necrosis Odds Ratio Reproducibility of Results Severity of Illness Index* Technetium Tc 99m Sestamibi / diagnostic use* Tomography, Emission-Computed, Single-Photon* / standards |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 109581-73-9/Technetium Tc 99m Sestamibi |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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