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Comparison of patient acceptance of sodium phosphate versus polyethylene glycol plus sodium picosulfate for colon cleansing in Japanese.
MedLine Citation:
PMID:  22646064     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background and aim:  In Japan, patient acceptance of bowel preparation methods before colonoscopy remains unknown. This study was conducted to evaluate the patient acceptance of sodium phosphate (NaP) tablets and polyethylene glycol solution (PEG) with sodium picosulfate. Methods:  One hundred patients were randomized into 1 of the following 2 groups: the NaP tablet first-use group or the PEG with sodium picosulfate first-use group in a crossover design trial. Patient acceptance and incidence of adverse events were evaluated using a questionnaire. Colon cleansing effectiveness was also evaluated. Results:  Patients' overall impressions of the preparations were significantly different between the NaP tablet (77.9%, 67/86) and PEG with sodium picosulfate (60.5%, 52/86; P= 0.001). Nausea incidence as an adverse event was significantly different between the 2 regimens (P= 0.03). Colon cleansing effectiveness was not significantly different between the 2 regimens. Conclusions:   The results of this crossover study showed that patient acceptance was similar to those previously reported in a parallel-group comparison. In Japanese patients, preference for and acceptance of NaP tablets was significantly higher than those of PEG with sodium picosulfate solution. © 2012 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd.
Authors:
Naoki Hosoe; Manabu Nakashita; Hiroyuki Imaeda; Tomohisa Sujino; Rieko Bessho; Riko Ichikawa; Nagamu Inoue; Takanori Kanai; Toshifumi Hibi; Haruhiko Ogata
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-31
Journal Detail:
Title:  Journal of gastroenterology and hepatology     Volume:  -     ISSN:  1440-1746     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8607909     Medline TA:  J Gastroenterol Hepatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd.
Affiliation:
Center for Diagnostic and Therapeutic Endoscopy (N. H., N. I., and H. O.), Division of Gastroenterology and Hepatology, Department of Internal Medicine (M.N., T. S., R. B., R. I., T. K., and T. H.), School of Medicine, Keio University, Tokyo, Japan. Department of Internal medicine , Keiyu-hospital, Yokohama, Japan( M.N.) Department of General Internal Medicine, Saitama Medical University, Saitama, Japan. (H. I.).
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