| Comparison of oxygen cost of breathing with pressure-support ventilation and biphasic intermittent positive airway pressure ventilation. | |
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MedLine Citation:
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PMID: 9751587 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To assess the oxygen cost of breathing with either pressure-support ventilation (PSV) or biphasic intermittent positive airway pressure ventilation (BIPAP). DESIGN: Prospective, randomized, crossover study. SETTING: Medical intensive care unit of a university hospital. PATIENTS: Twenty clinically stable and spontaneously breathing patients after long-term mechanical ventilation. INTERVENTIONS: Patients were randomized to start on either PSV or BIPAP, and measurements were performed after an adaptation period of 30 mins. Immediately after, the ventilatory mode was changed and after another 30-min adaptation period, the same measurements were performed. MEASUREMENTS AND MAIN RESULTS: Indirect calorimetry was performed during each ventilatory mode for a period of 30 mins. Oxygen consumption, energy expenditure, CO2 production, and respiratory quotient did not differ significantly between the two ventilatory modes, regardless of the patients' randomization. There were no statistically significant differences with regard to respiratory rate, minute volume, and blood gas analysis. All patients tolerated both ventilatory modes without any signs of discomfort. CONCLUSIONS: Pressure support ventilation and BIPAP are both used for weaning patients gradually from the ventilator. BIPAP may be advantageous in patients not breathing sufficiently with PSV, since no patient effort is necessary with use of this ventilatory mode. |
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Authors:
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T Staudinger; H Kordova; M Röggla; P Tesinsky; G J Locker; K Laczika; S Knapp; M Frass |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Critical care medicine Volume: 26 ISSN: 0090-3493 ISO Abbreviation: Crit. Care Med. Publication Date: 1998 Sep |
Date Detail:
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Created Date: 1998-10-08 Completed Date: 1998-10-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0355501 Medline TA: Crit Care Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1518-22 Citation Subset: AIM; IM |
Affiliation:
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Department of Internal Medicine, University of Vienna, Austria. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Calorimetry, Indirect Cross-Over Studies Energy Metabolism Female Humans Intermittent Positive-Pressure Ventilation* / methods Male Middle Aged Oxygen Consumption* Prospective Studies Work of Breathing* |
| Comments/Corrections | |
Comment In:
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Crit Care Med. 2000 May;28(5):1691-2
[PMID:
10834757
]
Crit Care Med. 1998 Sep;26(9):1473-4 [PMID: 9751574 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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