Document Detail

Comparison of overnight pooled and standard sputum collection method for patients with suspected pulmonary tuberculosis in northern Tanzania.
MedLine Citation:
PMID:  22567273     Owner:  NLM     Status:  PubMed-not-MEDLINE    
In Tanzania sputum culture for tuberculosis (TB) is resource intensive and available only at zonal facilities. In this study overnight pooled sputum collection technique was compared with standard spot morning collection among pulmonary TB suspects at Kibong'oto National TB Hospital in Tanzania. A spot sputum specimen performed at enrollment, an overnight pooled sputum, and single morning specimen were collected from 50 subjects and analyzed for quality, quantity, and time to detection in Bactec MGIT system. Forty-six (92%) subjects' overnight pooled specimens had a volume ≥5 mls compared to 37 (37%) for the combination of spot and single morning specimens (P < 0.001). Median time to detection was 96 hours (IQR 87-131) for the overnight pooled specimens compared to 110.5 hours (IQR is 137 right 137-180) for the combination of both spot and single morning specimens (P = 0.001). In our setting of limited TB culture capacity, we recommend a single pooled sputum to maximize yield and speed time to diagnosis.
Stellah G Mpagama; Charles Mtabho; Solomon Mwaigwisya; Liberate J Mleoh; I Marion Sumari-de Boer; Scott K Heysell; Eric R Houpt; Gibson S Kibiki
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Publication Detail:
Type:  Journal Article     Date:  2012-01-19
Journal Detail:
Title:  Tuberculosis research and treatment     Volume:  2012     ISSN:  2090-1518     ISO Abbreviation:  Tuberc Res Treat     Publication Date:  2012  
Date Detail:
Created Date:  2012-05-08     Completed Date:  2012-08-23     Revised Date:  2014-04-30    
Medline Journal Info:
Nlm Unique ID:  101576351     Medline TA:  Tuberc Res Treat     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  128057     Citation Subset:  -    
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