Document Detail


Comparison of outcomes in acute coronary syndrome in patients receiving statins within 24 hours of onset versus at later times.
MedLine Citation:
PMID:  15518612     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The clinical benefits of statins in acute coronary syndromes are well established, but the optimal time for administration in this setting has not been well studied. In this study, patients who had acute coronary syndrome and received statins <24 hours of presentation had lower incidences of death, stroke, reinfarction, heart failure, and pulmonary edema compared with delayed administration. Prompt administration of statins appears to be significantly beneficial in patients who present with an acute coronary syndrome.
Authors:
Fadi A Saab; Kim A Eagle; Eva Kline-Rogers; Jianming Fang; Richard Otten; Debabrata Mukherjee;
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  94     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-11-02     Completed Date:  2005-01-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1166-8     Citation Subset:  AIM; IM    
Affiliation:
University of Michigan Cardiovascular Center, Ann Arbor, Michigan 48109-0311, USA.
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MeSH Terms
Descriptor/Qualifier:
Adrenergic beta-Antagonists / therapeutic use
Aged
Angina, Unstable / drug therapy,  mortality
Angiotensin-Converting Enzyme Inhibitors / therapeutic use
Coronary Disease / drug therapy*,  mortality
Female
Follow-Up Studies
Hospital Mortality
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
Male
Michigan
Middle Aged
Multivariate Analysis
Myocardial Infarction / drug therapy,  mortality
Syndrome
Time Factors
Treatment Outcome
Chemical
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Angiotensin-Converting Enzyme Inhibitors; 0/Hydroxymethylglutaryl-CoA Reductase Inhibitors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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