| Comparison of outcomes in ST-segment depression and ST-segment elevation myocardial infarction patients treated with emergency PCI: data from a multicentre registry. | |
| | |
MedLine Citation:
|
PMID: 23108517 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
BACKGROUND: Traditionally, acute myocardial infarction (AMI) has been described as either STEMI (ST-elevation myocardial infarction) or non-STEMI myocardial infarction. This classification is historically related to the use of thrombolytic therapy, which is effective in STEMI. The current era of widespread use of coronary angiography (CAG), usually followed by primary percutaneous coronary intervention (PCI) puts this classification system into question. OBJECTIVES: To compare the outcomes of patients with STEMI and ST-depression myocardial infarction (STDMI) who were treated with emergency PCI. METHODS: This multicentre registry enrolled a total of 6 602 consecutive patients with AMI. Patients were divided into the following subgroups: STEMI (n = 3446), STDMI (n = 907), left bundle branch block (LBBB) AMI (n = 241), right bundle branch block (RBBB) AMI (n = 338) and other electrocardiographic (ECG) AMI (n = 1670). Baseline and angiographic characteristics were studied, and revascularisation therapies and in-hospital mortality were analysed. RESULTS: Acute heart failure was present in 29.5% of the STDMI vs 27.4% of the STEMI patients (p < 0.001). STDMI patients had more extensive coronary atherosclerosis than patients with STEMI (three-vessel disease: 53.1 vs 30%, p < 0.001). The left main coronary artery was an infract-related artery (IRA) in 6.0% of STDMI vs 1.1% of STEMI patients (p < 0.001). TIMI flow 0-1 was found in 35.0% of STDMI vs 66.0% of STEMI patients (p < 0.001). Primary PCI wasperformed in 88.1% of STEMI (with a success rate of 90.8%) vs 61.8% of STDMI patients (with a success rate of 94.5%) (p = 0.012 for PCI success rates). In-hospital mortality was not significantly different (STDMI 6.3 vs STEMI 5.4%, p = 0.330). CONCLUSION: These data suggest that similar strategies (emergency CAG with PCI whenever feasible) should be applied to both these types of AMI. |
| | |
Authors:
|
Jiri Knot; Petr Kala; Richard Rokyta; Josef Stasek; Boyko Kuzmanov; Ota Hli Nomaz; Jan Bĕlohlavek; Fili P Rohac; Robert Petr; Dana Bil Kova; Slavejko Djambazov; Mladen Grigorov; Petr Widimsky |
Related Documents
:
|
18082527 - Survey of current practices of the specialty of physicians interpreting cardiac and non... 23144177 - Predictive value of neutrophil to lymphocyte ratio in clinical outcomes of non-st eleva... 18064337 - Interleukin 6 plasma levels predict with high sensitivity and specificity coronary sten... 23595087 - Duraheart(tm) magnetically levitated left ventricular assist device. 22111737 - A prospective natural-history study of coronary atherosclerosis. 20833647 - Cardiac-specific leptin receptor deletion exacerbates ischaemic heart failure in mice. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Cardiovascular journal of Africa Volume: 23 ISSN: 1680-0745 ISO Abbreviation: Cardiovasc J Afr Publication Date: 2012 Oct |
Date Detail:
|
Created Date: 2012-10-30 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101313864 Medline TA: Cardiovasc J Afr Country: South Africa |
Other Details:
|
Languages: eng Pagination: 495-500 Citation Subset: IM |
Affiliation:
|
Third Faculty of Medicine, Charles University, Prague, Czech Republic. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A comparative study of amoxicillin, clindamycin and chlorhexidine in the prevention of post-extracti...
Next Document: Elevated salivary C-reactive protein predicted by low cardio-respiratory fitness and being overweigh...