Document Detail

Comparison of operative mortality and morbidity for initial and repeat coronary artery bypass grafting: The Coronary Artery Surgery Study (CASS) registry experience.
MedLine Citation:
PMID:  6391399     Owner:  NLM     Status:  MEDLINE    
The National Heart, Lung, and Blood Institute's Coronary Artery Surgery Study (CASS) registry population was reviewed to allow comparison of operative mortality and morbidity rates for initial and repeat coronary artery bypass grafting (CABG) procedures. Standardized data collection was employed in CASS during patient entry (July 1, 1974, to May 31, 1979) and follow-up (ended November 30, 1982). Initial CABG was performed on 9,369 patients. Mean follow-up was 60.5 months. Repeat CABG was required in 283 patients (3.0%). The mean interval between operations was 39.3 months. Individuals needing reoperation tended to be young (p less than 0.0001) and female (p less than 0.002) and to have less extensive coronary artery disease (p less than or equal to 0.0001), less left ventricular impairment (p less than 0.0001), less evidence of congestive heart failure (p = 0.006), and fewer coronary vessel systems bypassed at the first operation (p less than 0.0001). Repeat CABG carried an increased risk of death compared with initial CABG (5.3% versus 3.1%, respectively; p less than 0.05). However, the rates of perioperative myocardial infarction (6.4% for repeat and 5.8% for initial CABG) and of all surgical complications combined (30.6% versus 27.9%) were not significantly different from those at initial CABG.
E D Foster; L D Fisher; G C Kaiser; W O Myers
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  38     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1984 Dec 
Date Detail:
Created Date:  1985-01-15     Completed Date:  1985-01-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  563-70     Citation Subset:  AIM; IM    
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MeSH Terms
Clinical Trials as Topic
Coronary Artery Bypass / adverse effects*,  mortality
Middle Aged
National Institutes of Health (U.S.)
Random Allocation
Reoperation / adverse effects,  mortality
United States

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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