Document Detail


Comparison of operant escape and innate reflex responses to nociceptive skin temperatures produced by heat and cold stimulation of rats.
MedLine Citation:
PMID:  15174941     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In behavioral tests, rats performed learned escape responses to thermal stimulation of the paws by 44.0. 47.0. or 0.3 degrees C. Licking, guarding, and jumping reflexes were evaluated at these temperatures. The frequency, latency, and duration of escape and reflex responses were compared and were related to hind-paw skin temperatures measured during stimulation of awake and anesthetized rats. The duration and latency of escape from heat were appropriately related to stimulus intensity. Escape occurred reliably for each intensity. Reflexes occurred unreliably and at long latency to 44.0 or 0.3 degrees C and were not appropriately related to heat intensity. The reflexes were relatively insensitive to thermal nociceptive stimulation other than heating of the skin at a high rate.
Authors:
Charles J Vierck; Robert Kline; Ronald G Wiley
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Behavioral neuroscience     Volume:  118     ISSN:  0735-7044     ISO Abbreviation:  Behav. Neurosci.     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-06-03     Completed Date:  2004-07-19     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8302411     Medline TA:  Behav Neurosci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  627-35     Citation Subset:  IM    
Copyright Information:
((c) 2004 APA, all rights reserved)
Affiliation:
Department of Neuroscience, University of Florida College of Medicine, Gainesville, FL 32610, USA. vierck@mbi.ufl.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Behavior, Animal
Capsaicin / pharmacology
Cold Temperature* / adverse effects
Conditioning, Operant / physiology*
Escape Reaction / physiology*
Female
Hot Temperature* / adverse effects
Nociceptors / physiology
Pain Measurement
Pain Threshold / drug effects,  physiology
Rats
Rats, Long-Evans
Reaction Time / physiology
Reflex / physiology*
Skin Temperature / physiology
Grant Support
ID/Acronym/Agency:
NS 07261/NS/NINDS NIH HHS
Chemical
Reg. No./Substance:
404-86-4/Capsaicin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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