| Comparison of one- and two-dimensional programmes for predicting the state of skin burns. | |
| | |
MedLine Citation:
|
PMID: 11834326 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To understand and accurately predict tissue damage following a burn, bioheat transfer based mathematical models of the skin were developed. First, mathematical equations with multiple factors to represent the different properties of the various layers of the skin were formulated. These equations were then numerically solved using finite-difference (1-D) and finite-element (2-D) analysis. By application of a standard Arrhenius model for damage rate, the extent of burn injury was computed from the transient temperature solution. The study of the thermal efficacy of cooling treatment was done. Numerical results calculated by current 1-D and 2-D models were compared and discussed. Temperature contours were found to be consistent in both one- and two-dimensions. The current finite element code provided some additional precision to previously published models as a mesh independent grid was used to enable more accurate numerical prediction of thermal and injury patterns as they developed during the injury process. The study of thermal efficacy of postburn therapy showed that postburn water-cooling could not effectively reduce the extent of burn. However, low temperatures may inhibit the action of inflammatory mediators, and/or, low-temperatures may depress metabolism or microvascular flow thereby reducing long-term injury. Therefore numerical data obtained in the current study suggest that non-thermal factors must be considered in the calculation of the efficacy of postburn cooling therapy. It is equally important to realize that when dealing with living tissue, any numerical model can provide only an approximate to conditions in actual life. |
| | |
Authors:
|
E Y K Ng; L T Chua |
Related Documents
:
|
10217886 - Automatic detection of intraoperative neurological injury. 8361716 - Lifting weights. 21975256 - Using existing data to predict and quantify the risks of gm forage to a population of a... 15284556 - The applicability of a computer model for predicting head injury incurred during actual... 11082236 - Risk-indifferent foraging behaviour in honeybees. 23465896 - The cellulose resource matrix. |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Burns : journal of the International Society for Burn Injuries Volume: 28 ISSN: 0305-4179 ISO Abbreviation: Burns Publication Date: 2002 Feb |
Date Detail:
|
Created Date: 2002-02-08 Completed Date: 2002-04-25 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8913178 Medline TA: Burns Country: England |
Other Details:
|
Languages: eng Pagination: 27-34 Citation Subset: IM |
Affiliation:
|
School of Mechanical & Production Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore. mykng@ntu.edu.sg |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Burns
/
physiopathology*,
therapy* Cryotherapy* Finite Element Analysis Humans Models, Theoretical Outcome Assessment (Health Care)* Predictive Value of Tests Severity of Illness Index Skin / injuries*, physiopathology* Software* Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The treatment of Lewisite burns with laser debridement---'lasablation'.
Next Document: Ruthenium red attenuated cardiomyocyte and mitochondrial damage during the early stage after severe ...