Document Detail

Comparison of nonlinear methods symbolic dynamics, detrended fluctuation, and Poincare plot analysis in risk stratification in patients with dilated cardiomyopathy.
MedLine Citation:
PMID:  17411277     Owner:  NLM     Status:  MEDLINE    
Dilated cardiomyopathy (DCM) has an incidence of about 20100 000 new cases per annum and accounts for nearly 10 000 deaths per year in the United States. Approximately 36% of patients with dilated cardiomyopathy (DCM) suffer from cardiac death within five years after diagnosis. Currently applied methods for an early risk prediction in DCM patients are rather insufficient. The objective of this study was to investigate the suitability of short-term nonlinear methods symbolic dynamics (STSD), detrended fluctuation (DFA), and Poincare plot analysis (PPA) for risk stratification in these patients. From 91 DCM patients and 30 healthy subjects (REF), heart rate and blood pressure variability (HRV, BPV), STSD, DFA, and PPA were analyzed. Measures from BPV analysis, DFA, and PPA revealed highly significant differences (p<0.0011) discriminating REF and DCM. For risk stratification in DCM patients, four parameters from BPV analysis, STSD, and PPA revealed significant differences between low and high risk (maximum sensitivity: 90%, specificity: 90%). These results suggest that STSD and PPA are useful nonlinear methods for enhanced risk stratification in DCM patients.
Andreas Voss; Rico Schroeder; Sandra Truebner; Matthias Goernig; Hans Reiner Figulla; Alexander Schirdewan
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chaos (Woodbury, N.Y.)     Volume:  17     ISSN:  1054-1500     ISO Abbreviation:  Chaos     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-04-06     Completed Date:  2007-06-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100971574     Medline TA:  Chaos     Country:  United States    
Other Details:
Languages:  eng     Pagination:  015120     Citation Subset:  IM    
Department of Medical Engineering, University of Applied Sciences Jena, Carl-Zeiss-Promenade 2, D-07745 Jena, Germany.
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MeSH Terms
Blood Pressure
Blood Pressure Determination / methods*
Cardiomyopathy, Dilated / diagnosis*,  physiopathology*
Diagnosis, Computer-Assisted / methods*
Electrocardiography / methods*
Heart Rate
Middle Aged
Nonlinear Dynamics
Oscillometry / methods*
Reproducibility of Results
Risk Assessment / methods*
Risk Factors
Sensitivity and Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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