| Comparison of a new and a standard single-needle dialysis system using a mathematical model. | |
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MedLine Citation:
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PMID: 8507168 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two single-needle dialysis systems are compared for their hydrodynamic and kinetic behavior, the classic double-headed pump system and a newer bidirectional blood pump. First, discharges and pressures are calculated in a time-space grid to learn about the flow characteristics of the single-needle systems. These parameters are important for they control ultrafiltration and clearance rates in the artificial kidney. Also, the influence of different artificial kidneys and expansion chambers on the flow parameters is studied. Second, starting from these results, the removal of urea and creatinine is simulated using a double-pool model for both a normal dialysis session and an ultrashort daily autodialysis. As a result, the use of a single marker molecule to study or characterize solute removal is questioned. The new blood pump is able to perform dialysis filtering equivalently to the classic system but has its own specific advantages. |
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Authors:
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D De Wachter; P Verdonck; R Verhoeven; R Hombrouckx |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Artificial organs Volume: 17 ISSN: 0160-564X ISO Abbreviation: Artif Organs Publication Date: 1993 May |
Date Detail:
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Created Date: 1993-07-07 Completed Date: 1993-07-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7802778 Medline TA: Artif Organs Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 328-38 Citation Subset: IM |
Affiliation:
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Hydraulics Laboratory, University of Ghent, Belgium. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Creatinine
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metabolism Humans Kidney, Artificial* Models, Biological Models, Theoretical Needles Urea / metabolism |
| Chemical | |
Reg. No./Substance:
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57-13-6/Urea; 60-27-5/Creatinine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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