Document Detail

Comparison of myocardial damage from defibrillator discharges at various dosages.
MedLine Citation:
PMID:  7354738     Owner:  NLM     Status:  MEDLINE    
To study the difference in myocardial damage produced by the same defibrillation energy delivered at frequent, low-energy discharges vs infrequent, high-energy discharges, experiments were performed on 48 dogs. In Part I, a total of 3000 Wsec energy was delivered; in Part II, a total of 600 Wsec was delivered; and in Parts III and IV, a total of 1800 Wsec was delivered. In half the dogs, the energy was delivered in three shocks within 135 sec. In the other half, the shocks were delivered by 10 smaller shocks at 15-sec intervals. The degree of myocardial damage assessed by ST-segment elevation on precordial mapping or necrotic index from gross and microscopic examination 4 days after the shocks showed no significant difference. However, the three high-energy shocks (600 to 100 Wsec) resulted in ventricular fibrillation or complete heart block in 33% (6 of 18) of the dogs. These arrhythmias were not observed in the animals receiving low-energy (60-, 200-, or 300-Wsec) discharges.
G A Ewy; D Taren; J Bangert; S McClung; D A Hellman
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Medical instrumentation     Volume:  14     ISSN:  0090-6689     ISO Abbreviation:  Med Instrum     Publication Date:    1980 Jan-Feb
Date Detail:
Created Date:  1980-04-25     Completed Date:  1980-04-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0361136     Medline TA:  Med Instrum     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  9-12     Citation Subset:  IM    
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MeSH Terms
Cardiomyopathies / etiology*,  pathology
Electric Countershock / adverse effects*,  methods
Heart Block / etiology
Myocardium / pathology
Necrosis / pathology
Ventricular Fibrillation / etiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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