| Comparison of multislice computed tomography with intravascular ultrasound for detection and characterization of coronary artery plaques: a systematic review. | |
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MedLine Citation:
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PMID: 18586427 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Multislice computed tomography (MSCT) is a novel non-invasive test for detection and analysis of coronary artery plaques. A systematic review was conducted of the literature to compare MSCT with IVUS as the reference standard for assessing coronary artery plaques. MATERIALS AND METHODS: We performed a literature search in the online database MEDLINE, which was accessed at http://www.pubmed.gov on 9th April 2008. RESULTS: The search identified 14 studies with 340 patients (mean age 59+/-5 years). The systematic review revealed a sensitivity of MSCT on the lesion level (n=1779 coronary plaques) on the order of 90% (range from 87 to 92%) in comparison to IVUS. Per-segment analysis (n=356) yielded a lower sensitivity of 81-86%. In the per-vessel analysis (n=90), MSCT had a better sensitivity and specificity for the RCA (83-89% and 92-100%) and the LAD (83-87% and 93%) than for the LCX (71-85% and 77-89%), and on the vessel level and the cross-section analysis MSCT was more sensitive for calcified plaques than for non-calcified plaque. It is noteworthy that most studies provide only incomplete data on technical and methodological parameters such as radiation exposure and patient characteristics. CONCLUSION: MSCT is an accurate and reliable test for detection of coronary artery plaques in comparison to IVUS with limitations in regards to the LCX and non-calcified plaques. Studies published thus far are limited by the sample sizes and methodological quality issues. |
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Authors:
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Ivonne Springer; Marc Dewey |
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Publication Detail:
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Type: Comparative Study; Journal Article; Meta-Analysis; Review Date: 2008-06-30 |
Journal Detail:
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Title: European journal of radiology Volume: 71 ISSN: 1872-7727 ISO Abbreviation: Eur J Radiol Publication Date: 2009 Aug |
Date Detail:
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Created Date: 2009-08-03 Completed Date: 2009-10-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8106411 Medline TA: Eur J Radiol Country: Ireland |
Other Details:
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Languages: eng Pagination: 275-82 Citation Subset: IM |
Affiliation:
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Department of Radiology, Charité, Medical School, Humboldt-Universität zu Berlin, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Coronary Angiography
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methods* Coronary Artery Disease / diagnosis* Echocardiography / methods* Humans Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray Computed / methods* Ultrasonography, Interventional / methods* |
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