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Comparison of mortality and morbidity in multiple versus singleton very low birth weight infants in a neonatal intensive care unit.
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MedLine Citation:
PMID:  14676431     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Multiple births in Korea have been increased recently as a consequence of increased infertility due to advancing maternal age at first birth, and increased use of assisted reproductive technology. Multiples suffer higher mortality and morbidity than singletons. However, it is not clear whether preterm multiple very low birth weight infants (VLBWI) suffer higher mortality and morbidity than comparable singletons. We evaluated 266 singleton and 113 multiple VLBWI to determine whether mortality and morbidity in multiple VLBWI were higher than those in comparable singletons. The rate of in vitro fertilization and cesarean section were significantly higher in multiples than singletons. The total and the adjusted mortality with gestational age and birth weight were not significantly different between the two groups. Maternal age and the incidence of respiratory distress syndrome, patent ductus arteriosus, bronchopulmonary dysplasia, intracranial hemorrhage (grade> or =3), cystic periventricular leukomalacia, and retinopathy of prematurity (stage> or =3) were not significantly different between the two groups, and the incidence of abnormal brainstem auditory evoked potential was higher among the singletons. These results suggest that multiple VLBWI do not suffer higher mortality or morbidity than comparable singletons.
Authors:
Kye Hyang Lee; Soo Jung Hwang; Sung Hye Kim; Soo Hyun Lee; Dong Kil Yu; Jong Hee Hwang; Chang Won Choi; Jae Won Shim; Yun Sil Chang; Won Soon Park
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of Korean medical science     Volume:  18     ISSN:  1011-8934     ISO Abbreviation:  J. Korean Med. Sci.     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-12-16     Completed Date:  2004-08-05     Revised Date:  2011-03-16    
Medline Journal Info:
Nlm Unique ID:  8703518     Medline TA:  J Korean Med Sci     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  779-82     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
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MeSH Terms
Descriptor/Qualifier:
Birth Weight
Female
Gestational Age
Humans
Infant
Infant Mortality*
Infant, Newborn
Infant, Very Low Birth Weight*
Intensive Care Units, Neonatal*
Korea
Maternal Age
Morbidity
Pregnancy
Pregnancy Outcome*
Pregnancy, Multiple*
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): J Korean Med Sci
Journal ID (pmc): jkms
ISSN: 1011-8934
ISSN: 1598-6357
Publisher: Korean Academy of Medical Sciences
Article Information
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Print publication date: Month: 12 Year: 2003
Volume: 18 Issue: 6
First Page: 779 Last Page: 782
ID: 3055134
PubMed Id: 14676431
Publisher Item Identifier: 200312779

Comparison of mortality and morbidity in multiple versus singleton very low birth weight infants in a neonatal intensive care unit.
Kye Hyang Lee
Soo Jung Hwang
Sung Hye Kim
Soo Hyun Lee
Dong Kil Yu
Jong Hee Hwang
Chang Won Choi
Jae Won Shim
Yun Sil Chang
Won Soon Park
Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.


Article Categories:
  • Research Article


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