| Comparison of morphology and mechanical properties of PLGA bioscaffolds. | |
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MedLine Citation:
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PMID: 18458364 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this study, bioscaffolds using poly(DL-lactide-co-glycolide) acid (PLGA) were fabricated and studied. The gas foaming/salt leaching technique in a batch foaming setup was employed, and the effects of material composition of PLGA on the morphology and mechanical properties using this process were investigated. Two material compositions of PLGA 50/50 and 85/15 were used, and characterization of scaffolds fabricated with these materials showed that a lower relative density can be achieved with an increasing poly(DL-lactide) acid (PDLLA) content; however, higher open-cell porosity was obtained with lower PDLLA content. Furthermore, the effect of PLGA composition on modulus of the scaffolds was minor. |
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Authors:
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L Leung; C Chan; S Baek; Hani Naguib |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2008-04-15 |
Journal Detail:
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Title: Biomedical materials (Bristol, England) Volume: 3 ISSN: 1748-605X ISO Abbreviation: Biomed Mater Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-06-04 Completed Date: 2008-06-27 Revised Date: 2010-03-11 |
Medline Journal Info:
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Nlm Unique ID: 101285195 Medline TA: Biomed Mater Country: England |
Other Details:
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Languages: eng Pagination: 025006 Citation Subset: IM |
Affiliation:
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Department of Mechanical and Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, Ontario, M5S 3G8, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biocompatible Materials
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chemistry* Elasticity Lactic Acid / chemistry* Materials Testing Polyglycolic Acid / chemistry* Stress, Mechanical Surface Properties Tensile Strength Tissue Engineering / methods* |
| Chemical | |
Reg. No./Substance:
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0/Biocompatible Materials; 0/polylactic acid-polyglycolic acid copolymer; 26009-03-0/Polyglycolic Acid; 50-21-5/Lactic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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