| Comparison of magnetic resonance imaging-fluorodeoxy- glucose positron emission tomography fusion with pathological staging in rectal cancer. | |
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MedLine Citation:
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PMID: 20035542 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND:: This study represents an initial experience with combined magnetic resonance imaging (MRI) and [(18)F]fluorodeoxyglucose positron emission tomography (FDG PET) (MRI-PET fusion) in the primary staging of rectal carcinoma. METHODS:: A retrospective analysis of data recorded on patients with rectal cancer was undertaken. Patients requiring long-course radiotherapy were excluded. Chest radiography, abdominal computed tomography and endorectal ultrasonography were performed. In addition, MRI of the pelvis, whole-body FDG PET and MRI-PET fusion were carried out. All patients subsequently underwent anterior resection. RESULTS:: Twenty-three patients with rectal carcinoma (15 men), of median age 60 (range 46-75) years, were enrolled. In tumour (T) assessment, MRI correctly staged 14 of 22 T2/T3 tumours. In lymph node assessment, MRI-PET fusion had a sensitivity of 44 per cent, with a specificity and positive predictive value of 100 per cent. No additional information was acquired from MRI-PET fusion over MRI plus abdominal computed tomography and chest radiography. CONCLUSION:: MRI-PET fusion adds little to conventional investigations for staging rectal carcinoma. |
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Authors:
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M H Kam; D C Wong; S Siu; A R L Stevenson; J Lai; G E Phillips |
Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article |
Journal Detail:
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Title: The British journal of surgery Volume: 97 ISSN: 1365-2168 ISO Abbreviation: Br J Surg Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-01-25 Completed Date: 2010-02-18 Revised Date: 2010-07-19 |
Medline Journal Info:
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Nlm Unique ID: 0372553 Medline TA: Br J Surg Country: England |
Other Details:
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Languages: eng Pagination: 266-8 Citation Subset: AIM; IM |
Copyright Information:
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Copyright (c) 2009 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. |
Affiliation:
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Department of Surgery, Royal Brisbane and Women's Hospital, Queensland, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Female Fluorodeoxyglucose F18 / diagnostic use* Humans Magnetic Resonance Imaging / methods* Male Middle Aged Neoplasm Staging Positron-Emission Tomography / methods* Radiopharmaceuticals / diagnostic use* Rectal Neoplasms / diagnosis* Retrospective Studies Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
| Comments/Corrections | |
Comment In:
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Br J Surg. 2010 Jul;97(7):1151; author reply 1151
[PMID:
20632294
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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