| Comparison of lymphocyte populations in cutaneous and electrical burn patients: a clinical study. | |
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MedLine Citation:
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PMID: 10741587 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Immunosuppression following thermal injury has been noted in recent years. Both cellular and humoral immune systems have been reported to be affected. The present study aimed to compare the quantitative differences between cutaneous and electrical burn patients in respect to the partition and levels of lymphocyte populations. From March 1997 through February 1998, 15 patients with major thermal injury or high voltage electrical injury were included in this clinical prospective study. Blood samples were collected at three and seven days postburn. The evaluation of lymphocyte populations of patients was performed by SimulTest IMK plus. T cell and B cell populations, activated T cells, natural killer and helper T cell levels were all suppressed in both groups. Suppressor T cell levels were elevated in electrical burn group at both three and seven days. Therefore, CD 4/CD 8 ratios were more suppressed in electrical burn group. In conclusion, lymphocyte populations in electrical burn patients and also contributing factors which play important roles in the development of sepsis in both group need to be investigated further. |
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Authors:
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M Deveci; M Sengezer; M Bozkurt; M Eski; A Inal |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
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Title: Burns : journal of the International Society for Burn Injuries Volume: 26 ISSN: 0305-4179 ISO Abbreviation: Burns Publication Date: 2000 May |
Date Detail:
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Created Date: 2000-04-20 Completed Date: 2000-04-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8913178 Medline TA: Burns Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 229-32 Citation Subset: IM; X |
Affiliation:
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Department of Plastic and Reconstructive Surgery and Burn Centre, Gülhane Military Medical Academny, Ankara, Turkey. mdeveci98@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antigens, CD3 / analysis* Burns / immunology Burns, Electric / immunology* CD4 Lymphocyte Count CD4-CD8 Ratio CD4-Positive T-Lymphocytes* Female Humans Immune Tolerance / physiology Injury Severity Score Male Middle Aged Probability Prognosis Receptors, IgG / analysis* Skin / immunology, injuries* T-Lymphocyte Subsets* |
| Chemical | |
Reg. No./Substance:
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0/Antigens, CD3; 0/Receptors, IgG |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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