Document Detail

Comparison of long-term usefulness of clopidogrel therapy after the first percutaneous coronary intervention or coronary artery bypass grafting versus that after the second or repeat intervention.
MedLine Citation:
PMID:  15342293     Owner:  NLM     Status:  MEDLINE    
Patients in the Clopidogrel for the Reduction of Events During Observation trial were subgrouped according to whether they underwent index percutaneous coronary artery revascularization procedures only or this procedure plus subsequent percutaneous or surgical revascularization procedures during 1-year follow-up. The relative risk reduction in ischemic events associated with up-front and long-term clopidogrel compared with placebo was 2-fold greater in patients who required repeat revascularization procedures compared with those who did not (42.4% vs 21.7%).
Jacqueline Saw; Eric J Topol; Steven R Steinhubl; Danielle Brennan; Peter B Berger; David J Moliterno;
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of cardiology     Volume:  94     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-09-02     Completed Date:  2004-09-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  623-5     Citation Subset:  AIM; IM    
Copyright Information:
Copyright 2004 Excerpta Medica, Inc.
Department of Cardiovascular Medicine, the Cleveland Clinic Foundation, Cleveland, Ohio, USA.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary / methods*
Coronary Artery Bypass / methods*
Middle Aged
Myocardial Ischemia / therapy*
Platelet Aggregation Inhibitors / therapeutic use*
Randomized Controlled Trials as Topic
Risk Reduction Behavior
Ticlopidine / analogs & derivatives*,  therapeutic use*
Reg. No./Substance:
0/Platelet Aggregation Inhibitors; 55142-85-3/Ticlopidine; 90055-48-4/clopidogrel

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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