Document Detail


Comparison of long-term progestin-based estrus synchronization protocols in beef heifers.
MedLine Citation:
PMID:  20656979     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Two experiments evaluated long-term progestin-based estrus-synchronization programs on the basis of potential for use in facilitating fixed-time AI in estrous cycling and prepubertal beef heifers. In Exp. 1, heifers were assigned to 1 of 2 treatments by age, BW, and estrous cyclicity status. Heifers assigned to the melengestrol acetate-PGF(2α) protocol (MGA-PG; n = 50) received MGA (0.5 mg·animal(-1)·d(-1)) in a 1.0-kg carrier from d 0 to 13 and were administered PGF(2α) (25 mg, intramuscularly) 19 d after MGA withdrawal (d 32). Heifers assigned to the Show-Me-Synch protocol (n = 49) received a controlled internal drug release (CIDR) insert (1.38 g of progesterone) from d 2 to 16 followed by PGF(2α) administration 16 d after CIDR removal (d 32). All heifers were fitted with HeatWatch estrus-detection transmitters at the time of progestin removal for continuous estrus detection through the synchronized period after PGF(2α). In Exp. 2, heifers (n = 396) were assigned to the same 2 treatments described in Exp. 1 by age, BW, and reproductive tract score. Heifers in Exp. 2, however, were fitted with HeatWatch estrus-detection transmitters at PGF(2α) to characterize estrus-distribution patterns during the synchronized period after PGF(2α). Heifers in both experiments were inseminated approximately 12 h after the onset of estrus. In Exp. 1, estrous response after PGF(2α) and mean interval to estrus after PGF(2α) did not differ between MGA-PG and Show-Me-Synch treatments (P = 0.97). The variance for interval to estrus after PGF(2α) tended (P = 0.06) to be reduced among MGA-PG-treated heifers compared with Show-Me-Synch-treated heifers. Conception to AI, AI pregnancy, and final pregnancy rates did not differ (P > 0.1) between treatments. In Exp. 2, estrous response after PGF(2α) was greater (P = 0.01) among Show-Me-Synch-treated heifers (92%) compared with MGA-PG-treated heifers (85%); however, mean interval to estrus after PGF(2α) did not differ (P = 0.74) between MGA-PG (57.4 ± 2.5 h) and Show-Me-Synch (56.2 ± 2.5 h) treatments. The variance for interval to estrus after PGF(2α) was reduced (P < 0.01) among Show-Me-Synch-treated vs. MGA-PG-treated heifers. Conception to AI, AI pregnancy, and final pregnancy rates did not differ (P > 0.1) between treatments. In summary, the Show-Me-Synch protocol compared favorably with the MGA-PG protocol on the basis of estrous response, synchrony of estrus, and resulting fertility after treatment administration.
Authors:
D A Mallory; D J Wilson; D C Busch; M R Ellersieck; M F Smith; D J Patterson
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2010-07-23
Journal Detail:
Title:  Journal of animal science     Volume:  88     ISSN:  1525-3163     ISO Abbreviation:  J. Anim. Sci.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003002     Medline TA:  J Anim Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3568-78     Citation Subset:  IM    
Affiliation:
Division of Animal Science, S132 ASRC, University of Missouri, Columbia, 65211, USA.
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