| Comparison of lipase activity in peritoneal fluid of dogs with different pathologies--a complementary diagnostic tool in acute pancreatitis? | |
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MedLine Citation:
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PMID: 16533326 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A clinical diagnosis of acute pancreatitis is often difficult to obtain. Histopathology remains the gold standard, whereas clinical signs, diagnostic imaging and laboratory testing, even in combination, may be insufficient. In a prospective study, lipase activity in ascitic fluid of various aetiologies was determined in 44 dogs in order to investigate its performance in cases of acute pancreatitis. Data of simultaneously determined blood lipase activities were available in 27 dogs. Lipase activity was measured by a colorimetric assay. A complete peritoneal fluid analysis was performed. Dogs were divided into four groups, according to their final diagnosis: acute pancreatitis (A), abdominal trauma (B), abdominal neoplasia (C) and others (hepatic or cardiac diseases) (D). Dogs with acute pancreatitis had a significantly higher peritoneal lipase activity than those in other groups (P < or = 0.024), while no significant difference was found between the other groups (P > or = 0.734). Blood lipase activity as well as protein content and total cell count of the ascitic fluid did not show any significant difference between groups. Data show that determination of lipase activity in dogs that develop ascites may be useful in complementing the diagnosis of acute pancreatitis. |
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Authors:
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A Guija de Arespacochaga; K M Hittmair; I Schwendenwein |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine Volume: 53 ISSN: 0931-184X ISO Abbreviation: J Vet Med A Physiol Pathol Clin Med Publication Date: 2006 Apr |
Date Detail:
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Created Date: 2006-03-14 Completed Date: 2006-07-11 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100955112 Medline TA: J Vet Med A Physiol Pathol Clin Med Country: Germany |
Other Details:
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Languages: eng Pagination: 119-22 Citation Subset: IM |
Affiliation:
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Central Laboratory, University of Veterinary Medicine, Vienna, Austria. abigail.guija@vu-wien.ac.at |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Injuries
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diagnosis,
enzymology,
veterinary Abdominal Neoplasms / diagnosis, enzymology, veterinary Acute Disease Animals Ascites / enzymology Ascitic Fluid / enzymology* Biological Markers / blood, metabolism Colorimetry / methods, veterinary Diagnosis, Differential Dog Diseases / diagnosis*, enzymology Dogs Female Heart Diseases / diagnosis, enzymology, veterinary Lipase / metabolism* Liver Diseases / diagnosis, enzymology, veterinary Male Pancreatitis / diagnosis, enzymology, veterinary* |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; EC 3.1.1.3/Lipase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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